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Publication Name World Journal of Clinical Cases
Manuscript ID 120049
Country Taiwan
Category Oncology
Manuscript Type Case Report
Article Title Paget’s disease of the nipple with occult ductal carcinoma in situ despite negative conventional imaging: A case report
Manuscript Source Unsolicited Manuscript
All Author List Chih-Yan Tsai, Tzu-Chun Lo, Jyh-Cherng Yu, Zhi-Jie Hong and Yu-Kai Sung
Funding Agency and Grant Number
Corresponding Author Jyh-Cherng Yu, MD, Department of General Surgery, Tri-Service General Hospital, No. 325, Section 2, Chenggong Road, Neihu District, Taipei 114201, Taiwan. doc20106@mail.ndmutsgh.edu.tw
Key Words Paget’s disease of the nipple; Paget’s disease of the breast; Ductal carcinoma in situ; Magnetic resonance imaging; Occult malignancy; Imaging-pathology correlation; Case report
Core Tip Mammary Paget’s disease, also known as Paget’s disease of the breast, may present as chronic nipple eczema without a detectable underlying malignant lesion on conventional imaging. In this case, diagnosis required repeat biopsy and magnetic resonance imaging despite initially benign imaging findings. Clinicians should maintain a high index of suspicion and pursue histopathologic evaluation when unilateral nipple-areolar dermatitis persists, even in the absence of radiologic evidence of malignancy.
Citation Tsai CY, Lo TC, Yu JC, Hong ZJ, Sung YK. Paget’s disease of the nipple with occult ductal carcinoma in situ despite negative conventional imaging: A case report. World J Clin Cases 2026; In press
Received
2026-02-13 03:03
Peer-Review Started
2026-02-13 03:04
First Decision by Editorial Office Director
2026-03-06 09:06
Return for Revision
2026-03-06 09:06
Revised
2026-04-03 12:37
Publication Fee Transferred
2026-04-08 14:17
Second Decision by Editor
2026-04-22 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-04-22 04:11
Articles in Press
2026-04-22 04:11
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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