Publication Name	World Journal of Radiology
Manuscript ID	120056
Country	India

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Prospective Study
Article Title	Evaluation of bicuspid aortic valve-associated aortopathic changes using third-generation dual-source computed tomography
Manuscript Source	Invited Manuscript
All Author List	Salai Thanihaivel E, Arun Sharma, Mansi Verma, Rajesh Vijayvergiya and Manphool Singhal
Funding Agency and Grant Number
Corresponding Author	Arun Sharma, Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Department of Cardiovascular Radiology & Endovascular Interventions, All India Institute of Medical Sciences, New Delhi, 110029, India. drarungautam@gmail.com., Chandigarh 160012, Chandīgarh, India. drarungautam@gmail.com
Key Words	Bicuspid aortic valve; Aortic size index; Dual-source computed tomography; Aortopathy; Ascending aortic dilatation; Coarctation; Dissection
Core Tip	Bicuspid aortic valve (BAV) is a common congenital cardiac anomaly, frequently associated with aortopathy. Using third-generation dual-source computed tomography (CT) in 100 patients, we observed ascending aortic dilatation in 87% and identified a cohort-specific aortic size index threshold of 23.8 mm/m2 associated with CT-defined ascending aortic dilatation > 40 mm (sensitivity 84%, specificity 90%). Because ASI is mathematically derived from the ascending aortic diameter, it is best interpreted as a cohort-specific threshold rather than as independent validation of ASI as a predictor. CT measurements were larger than transthoracic echocardiography (mean difference 11.72 mm), although this difference likely reflects differences in measurement sites, measurement conventions, and inherent limitations of 2D echocardiography in BAV rather than simple underestimation alone. These preliminary findings support further evaluation of indexed measurements alongside absolute diameter thresholds in populations with smaller body habitus, and will require validation in independent multicentre cohorts with longitudinal outcomes.
Citation	Thanihaivel E S, Sharma A, Verma M, Vijayvergiya R, Singhal M. Evaluation of bicuspid aortic valve-associated aortopathic changes using third-generation dual-source computed tomography. World J Radiol 2026; In press

Received	2026-02-14 02:01
Peer-Review Started	2026-02-14 02:02
First Decision by Editorial Office Director	2026-03-26 10:25
Return for Revision	2026-03-26 10:25
Revised	2026-04-16 01:17
Publication Fee Transferred
Second Decision by Editor	2026-05-25 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-25 09:27
Articles in Press	2026-05-25 09:27
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8470 (online)
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