Publication Name	World Journal of Stem Cells
Manuscript ID	120083
Country	Italy

Category	Ophthalmology
Manuscript Type	Minireviews
Article Title	Stem cells in managing glaucoma
Manuscript Source	Invited Manuscript
All Author List	Francesco Cappellani, Matteo Capobianco, Federico Visalli, Alessandro Avitabile, Giuseppe Gagliano, Simonetta Gaia Nicolosi, Marieme Khouyyi, Fabiana D’Esposito, Caterina Gagliano and Marco Zeppieri
Funding Agency and Grant Number
Corresponding Author	Marco Zeppieri, Consultant, MD, PhD, Postdoc, Department of Ophthalmology, University Hospital of Udine, p. le S. Maria della Misericordia 15, Udine 33100, Italy. mark.zeppieri@asufc.sanita.fvg.it
Key Words	Stem cells; Retinal ganglion cells; Glaucoma; Neuroprotection; Induced pluripotent stem cells; Regenerative medicine; Mesenchymal stem cells
Core Tip	Glaucoma is widely acknowledged as a chronic neurodegenerative condition characterized by irreversible loss of retinal ganglion cells, leading to progressive visual deterioration despite good management of intraocular pressure. Stem cell-based approaches present an innovative regenerative framework by delivering neurotrophic support, immunomodulation, and possible cellular replacement. Experimental studies indicate that embryonic, induced pluripotent, and mesenchymal stem cells can extend the survival of retinal ganglion cells and alter the glaucomatous milieu. Despite significant obstacles, stem cell technologies may eventually enhance or transform existing glaucoma treatment protocols.
Citation	Cappellani F, Capobianco M, Visalli F, Avitabile A, Gagliano G, Nicolosi SG, Khouyyi M, D’Esposito F, Gagliano C, Zeppieri M. Stem cells in managing glaucoma. World J Stem Cells 2026; In press

Received	2026-02-14 01:58
Peer-Review Started	2026-02-14 02:01
First Decision by Editorial Office Director	2026-03-26 10:14
Return for Revision	2026-03-26 10:14
Revised	2026-03-30 15:06
Publication Fee Transferred
Second Decision by Editor	2026-04-27 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-07 07:47
Articles in Press	2026-05-07 07:47
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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