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Publication Name World Journal of Psychiatry
Manuscript ID 120085
DOI 10.5498/wjp.120085
Country China
Category Psychiatry
Manuscript Type Observational Study
Article Title Observations on dynamic brain network properties of emotional information processing in patients with depression and sex differences
Manuscript Source Unsolicited Manuscript
All Author List Jin-Xiang Wang, Hong-Sheng Zhang, Meng Liu, Jin Zhao, Yu-Feng Wang, Li-Juan Shen and Meng Zhang
Funding Agency and Grant Number
Funding Agency Grant Number
Henan Provincial Health Commission Medical Science and Technology Joint Research Project No. LHGJ20230530
Open Research Project in the Department of Psychiatry and Neurology, the Second Affiliated Hospital of Xinxiang Medical University No. XYEFYJSSJ-2023-06
Doctoral Research Startup Fund of the Second Affiliated Hospital of Xinxiang Medical University No. 1777
Corresponding Author Jin-Xiang Wang, PhD, Department of Clinical Psychology, The Second Affiliated Hospital of Henan Medical University, No. 207 Qianjin Road, Muye District, Xinxiang 453002, Henan Province, China. wangjinxiang2001@163.com
Key Words Dynamic brain networks; Depression; Gender differences; Emotional information processing; Resting-state functional magnetic resonance imaging
Core Tip This observational study included 90 patients with depression (45 men/45 women) and 30 healthy controls. Using resting-state functional magnetic resonance imaging and dynamic brain network analysis, we identified impaired network efficiency, modularity, and emotional regulation in depression, with sex-related patterns. Women showed enhanced default mode network inhibition, while men exhibited salience network-limbic segregation. These findings offer key neuroimaging evidence for sex-specific depression diagnostic criteria and treatments.
Citation Wang JX, Zhang HS, Liu M, Zhao J, Wang YF, Shen LJ, Zhang M. Observations on dynamic brain network properties of emotional information processing in patients with depression and sex differences. World J Psychiatry 2026; In press
Received
2026-04-10 10:01
Peer-Review Started
2026-04-10 10:01
First Decision by Editorial Office Director
2026-04-29 09:00
Return for Revision
2026-04-29 09:00
Revised
2026-05-15 14:29
Publication Fee Transferred
2026-05-21 11:21
Second Decision by Editor
2026-06-02 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-03 06:07
Articles in Press
2026-06-03 06:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3206 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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