Publication Name	World Journal of Hepatology
Manuscript ID	120153
DOI	10.4254/wjh.120153
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Saroglitazar ameliorates alcoholic liver disease and is associated with enhanced ethanol metabolism
Manuscript Source	Unsolicited Manuscript
All Author List	Suresh R Giri, Bibhuti Bhoi, Chitrang Trivedi, Akshyaya Rath, Vighnesh Jadhav, Sandip Palode, Ramchandra Ranvir, Ashvin Patel, Rajesh Sundar, Hiren Patel and Mukul R Jain
Funding Agency and Grant Number
Corresponding Author	Suresh R Giri, PhD, Zydus Research Centre, Zydus Lifesciences Limited, Sarkhej-Bavla Highway No. 8A, Moraiya, Ahmedabad 382213, Gujarat, India. sureshgiri@zyduslife.com
Key Words	Dual-peroxisome proliferator-activated receptor alpha/gamma agonist; Alcoholic liver disease; Saroglitazar; Alcohol metabolism; National Institute on Alcohol Abuse and Alcoholism mouse model
Core Tip	Alcoholic liver disease is one of the major causes of morbidity worldwide and there is an unmet need for a drug to prevent or treat this condition. Saroglitazar, which is approved in India for the treatment of metabolic dysfunction-associated steatotic liver disease and metabolic dysfunction-associated steatohepatitis, showed beneficial effect like reduction in alanine aminotransferase, aspartate aminotransferase and hepatic triglyceride in animal model of alcoholic liver disease. Saroglitazar effectively altered the alcohol metabolism markers, thus reducing the alcohol-induced liver damage.
Citation	Giri SR, Bhoi B, Trivedi C, Rath A, Jadhav V, Palode S, Ranvir R, Patel A, Sundar R, Patel H, Jain MR. Saroglitazar ameliorates alcoholic liver disease and is associated with enhanced ethanol metabolism. World J Hepatol 2026; In press DOI: https://doi.org/10.4254/wjh.120153
PDF	120153-in-press.pdf

Received	2026-02-24 09:46
Peer-Review Started	2026-02-24 09:47
First Decision by Editorial Office Director	2026-04-08 08:55
Return for Revision	2026-04-09 10:57
Revised	2026-04-23 10:22
Publication Fee Transferred
Second Decision by Editor	2026-06-15 02:44
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-15 09:21
Articles in Press	2026-06-15 09:21
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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