Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	120158
Country	China

Category	Anesthesiology
Manuscript Type	Clinical Trials Study
Article Title	Effect of propofol and remimazolam on post-induction hypotension in hypertensive patients undergoing laparoscopic cholecystectomy
Manuscript Source	Unsolicited Manuscript
All Author List	Yu-Ting Zhang and Shuan-Cheng Bai
Funding Agency and Grant Number	Funding Agency Grant Number the Zhongguancun Precision Medicine Foundation Project 2024-1--097
Corresponding Author	Shuan-Cheng Bai, Anesthesiology, Baotou Central Hospital, No. 61, Huancheng Road, Donghe District, Baotou City, Inner Mongolia, Baotou 014040, Inner Mongolia Autonomous Region, China. bsc0130@163.com
Key Words	Remimazolam; Propofol; Total intravenous anesthesia; Hypertensive patients; Laparoscopic cholecystectomy
Core Tip	This study compared the incidence of post-induction hypotension (PIH) and hemodynamic stability between remimazolam and propofol during total intravenous anesthesia in hypertensive patients undergoing laparoscopic cholecystectomy. Compared to propofol, remimazolam significantly reduced the incidence and duration of PIH and decreased the use of norepinephrine. Remimazolam also had a lower incidence of injection pain during induction and better early postoperative sedation scores. The results suggest that remimazolam provides better hemodynamic stability without affecting the anesthetic effect, making it of high clinical value.
Citation	Zhang YT, Bai SC. Effect of propofol and remimazolam on post-induction hypotension in hypertensive patients undergoing laparoscopic cholecystectomy. World J Gastrointest Surg 2026; In press

Received	2026-02-24 05:23
Peer-Review Started	2026-02-24 05:24
First Decision by Editorial Office Director	2026-03-02 09:07
Return for Revision	2026-03-03 07:45
Revised	2026-03-05 04:43
Publication Fee Transferred	2026-03-13 15:07
Second Decision by Editor	2026-04-08 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-08 09:41
Articles in Press	2026-04-08 09:41
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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