Publication Name	World Journal of Critical Care Medicine
Manuscript ID	120168
Country	Nepal

Category	Critical Care Medicine
Manuscript Type	Correspondence
Article Title	Letter to the Editor: Magnesium supplementation in sepsis: A promising metabolic resuscitation strategy
Manuscript Source	Invited Manuscript
All Author List	Damodar Paudel
Funding Agency and Grant Number
Corresponding Author	Damodar Paudel, Department of Medicine, Department of Internal Medicine Nepal Police Hospital, Maharagjung, Kathmandu, Nepal, <bold>Correspondence:</bold> Dr Damodar Paudel, Department of Medicine, Nepal Police Hospital, Maharjgunj, Kathmandu, Nepal. Email: <email>damodarpaudel@gmail.com</email>, Phone: <phone>+977-9851280510</phone>, kathmandu 44600, Bāgmatī, Nepal. damodarpaudel@gmail.com
Key Words	Sepsis; Magnesium supplementation; Lactate clearance; Mitochondrial dysfunction; Metabolic dysfunction
Core Tip	Magnesium is a key co factor in ATP synthesis and mitochondrial electron transport and plays an important role in immune metabolic regulation. Hypomagnesemia impairs cellular energy metabolism and contributes to lactate accumulation, while hepatic dysfunction further compromises lactate clearance. Together, these mechanisms may exacerbate lactic acidosis and worsen outcomes in septic patients.
Citation	Paudel D. Letter to the Editor: Magnesium supplementation in sepsis: A promising metabolic resuscitation strategy. World J Crit Care Med 2026; In press

Received	2026-02-24 07:24
Peer-Review Started	2026-02-24 07:25
First Decision by Editorial Office Director	2026-03-12 08:40
Return for Revision	2026-03-12 08:40
Revised	2026-03-30 18:29
Publication Fee Transferred
Second Decision by Editor	2026-04-24 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-24 09:06
Articles in Press	2026-04-24 09:06
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3141(online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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