Publication Name	World Journal of Hepatology
Manuscript ID	120213
Country	Australia

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Recurrence after surgery for hepatocellular carcinoma: “The seed and the soil” - a multicentre retrospective cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Conner Blackmore, Ian Lockart, Geovanny Gandy, Yuen Kang Joseph Yeoh, Ciara Flynn, David S Prince, Gregory Dore, Mark Danta, Jacob George, Maryam Alavi, Yasser Farooque, Behzad Hajarizadeh and Miriam T Levy
Funding Agency and Grant Number
Corresponding Author	Miriam T Levy, Associate Professor, Department of Gastroenterology, Liverpool Hospital, Corner Elizabeth and Goulburn St, Liverpool 2170, New South Wales, Australia. miriam.levy@health.nsw.gov.au
Key Words	Hepatocellular carcinoma; Prognostic prediction; Surgery; Recurrence; ALBI grade
Core Tip	Recurrence following curative liver resection for hepatocellular carcinoma (HCC) remains a major clinical challenge. In this multicentre retrospective cohort study, cirrhosis, albumin-bilirubin grade ≥ 2, and Barcelona Clinic Liver Cancer stage B/C were independently associated with recurrence. These findings highlight the importance of both tumour burden and underlying liver function when estimating postoperative recurrence risk. Improved preoperative risk stratification may support patient counselling and multidisciplinary decision-making in the management of HCC.
Citation	Blackmore C, Lockart I, Gandy G, Yeoh YKJ, Flynn C, Prince DS, Dore G, Danta M, George J, Alavi M, Farooque Y, Hajarizadeh B, Levy MT. Recurrence after surgery for hepatocellular carcinoma: “The seed and the soil” - a multicentre retrospective cohort study. World J Hepatol 2026; In press

Received	2026-02-24 09:23
Peer-Review Started	2026-02-24 09:25
First Decision by Editorial Office Director	2026-03-04 08:58
Return for Revision	2026-03-04 08:58
Revised	2026-03-16 11:10
Publication Fee Transferred	2026-03-25 11:03
Second Decision by Editor	2026-04-14 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-14 06:35
Articles in Press	2026-04-14 06:35
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5182 (online)
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