Publication Name	World Journal of Psychiatry
Manuscript ID	120218
DOI	10.5498/wjp.120218
Country	China

Category	Psychiatry
Manuscript Type	Minireviews
Article Title	Takotsubo syndrome: A review of psychobiological mechanisms and clinical practice interventions
Manuscript Source	Unsolicited Manuscript
All Author List	Shu-Yi Lang and Fei Xia
Funding Agency and Grant Number
Corresponding Author	Fei Xia, Associate Professor, PhD, Department of Cardiology, People’s Hospital of China Medical University (Liaoning Provincial People’s Hospital), No. 3 Wenyi Road, Shenhe District, Shenyang 110016, Liaoning Province, China. xf19870421@126.com
Key Words	Takotsubo cardiomyopathy; Psychobiological mechanisms; Psychological interventions; Stress; Clinical practice
Core Tip	Takotsubo cardiomyopathy is a stress-induced cardiac condition with significant psychobiological underpinnings. This review synthesizes evidence on the role of psychological factors, including anxiety and post-traumatic stress disorder, in Takotsubo cardiomyopathy pathogenesis and prognosis. It highlights diagnostic approaches integrating imaging and psychological assessments, and evaluates psychological interventions such as cognitive behavioral therapy and group support, which may improve outcomes. Ongoing controversies and future directions for personalized treatment are discussed, emphasizing the need for multidisciplinary management of this mind-heart disorder.
Citation	Lang SY, Xia F. Takotsubo syndrome: A review of psychobiological mechanisms and clinical practice interventions. World J Psychiatry 2026; In press DOI: https://doi.org/10.5498/wjp.120218
PDF	120218-in-press.pdf

Received	2026-03-13 10:10
Peer-Review Started	2026-03-13 10:10
First Decision by Editorial Office Director	2026-04-04 01:45
Return for Revision	2026-04-04 01:45
Revised	2026-04-13 11:32
Publication Fee Transferred	2026-04-20 10:16
Second Decision by Editor	2026-06-09 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-09 06:10
Articles in Press	2026-06-09 06:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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