Publication Name	World Journal of Psychiatry
Manuscript ID	120241
Country	China

Category	Psychiatry
Manuscript Type	Review
Article Title	Endocrine psychiatric comorbidity in metabolic disorders: Integrative mechanisms and traditional Chinese medicine
Manuscript Source	Unsolicited Manuscript
All Author List	Miao Yan, Han Yang, Di Cui and Yi-Shuo Zhang
Funding Agency and Grant Number
Corresponding Author	Yi-Shuo Zhang, School of Pharmaceutical Sciences, Changchun University of Chinese Medicine, No. 1035 Boshuo Road, Jingyue National High-Tech Industrial Development Zone, Changchun 130117, Jilin Province, China. 202400904@ccucm.edu.cn
Key Words	Metabolic-psychiatric comorbidity; Insulin resistance; Gut-brain-metabolic axis; Traditional Chinese medicine; Integrated care pathway
Core Tip	Endocrine-psychiatric comorbidity in metabolic disorders is conceptualised as a bidirectional, self-reinforcing state in which sleep and behavioural feasibility are clinically actionable leverage points that can shape metabolic trajectories. Traditional Chinese medicine is framed as adjunctive, module-targeted care, with pattern phenotyping used pragmatically for stratification rather than as a parallel diagnostic system. Credible integration requires paired metabolic and mental health endpoints, mediator tracking, and structured safety monitoring within an iterative care pathway.
Citation	Yan M, Yang H, Cui D, Zhang YS. Endocrine psychiatric comorbidity in metabolic disorders: Integrative mechanisms and traditional Chinese medicine. World J Psychiatry 2026; In press

Received	2026-03-13 10:16
Peer-Review Started	2026-03-13 10:16
First Decision by Editorial Office Director	2026-04-02 05:59
Return for Revision	2026-04-02 05:59
Revised	2026-04-17 15:33
Publication Fee Transferred
Second Decision by Editor	2026-05-29 03:01
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-29 04:34
Articles in Press	2026-05-29 04:34
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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