Publication Name	World Journal of Psychiatry
Manuscript ID	120249
Country	China

Category	Psychology
Manuscript Type	Retrospective Study
Article Title	Incidence, risk factors, and correlation with organ involvement of psychological disorders in patients with Sjögren’s syndrome
Manuscript Source	Unsolicited Manuscript
All Author List	Guang-Qiao He, Ci-Yuan Yu, Bi-Yuan Xu, Li-Yang Dai, Yao-Jing Li, Chong-Yang Liu and Jian-Ping Diao
Funding Agency and Grant Number
Corresponding Author	Jian-Ping Diao, Department of Rheumatology and Immunology, The Third Affiliated Hospital of Chongqing Medical University (Fangda Hospital), No. 1 Shuanghu Branch Road, Huixing Street, Chongqing 401120, China. 651242@hospital.cqmu.edu.cn
Key Words	Sjögren’s syndrome; Mental disorders; Depression; Anxiety; Organ manifestations
Core Tip	Psychological disorders are Sjögren’s syndrome (SS), patient subjective stress inventory more than half of the studied population. Higher disease activity, longer disease duration and multi-organ involvement (especially interstitial lung disease and peripheral neuropathy) are closely tied with depression and anxiety. Quality of life correlates negatively, whereas psychological severity correlates positively with inflammatory markers. Independent risk factors included female sex and EULAR SS Disease Activity Index ≥ 12. These results demonstrate the two-way interaction between immune-mediated inflammation and mental health, indicating that regular psychological assessment alongside integrated multidisciplinary management of SS patients is warranted.
Citation	He GQ, Yu CY, Xu BY, Dai LY, Li YJ, Liu CY, Diao JP. Incidence, risk factors, and correlation with organ involvement of psychological disorders in patients with Sjögren’s syndrome. World J Psychiatry 2026; In press

Received	2026-03-17 10:08
Peer-Review Started	2026-03-17 10:09
First Decision by Editorial Office Director	2026-04-10 07:43
Return for Revision	2026-04-10 07:43
Revised	2026-05-12 15:38
Publication Fee Transferred	2026-05-14 08:08
Second Decision by Editor	2026-05-27 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-27 06:22
Articles in Press	2026-05-27 06:22
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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