Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	120263
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Opinion Review
Article Title	Reframing endoscopic screening in upper gastrointestinal cancers: From early detection to precision primary prevention
Manuscript Source	Invited Manuscript
All Author List	Jing Shi, Yun-Dong Shi and Ying-Hui Chen
Funding Agency and Grant Number
Corresponding Author	Yun-Dong Shi, Professor, Department of Nephropathy, Jilin People’s Hospital, Jilin City Hospital, Zhongxing Street, Jilin City 132000, Jilin Province, China. drshiyundong@163.com
Key Words	Upper gastrointestinal cancer; Endoscopic screening; Primary prevention; Precision prevention; Behavioral modification; Risk stratification; Cancer control
Core Tip	Endoscopic screening for upper gastrointestinal cancers has traditionally been regarded as a secondary prevention tool focused on early detection. Emerging evidence suggests that screening participation may facilitate behavioral risk modification and enhanced risk awareness, suggesting a potential paradigm shift toward precision primary prevention. By integrating behavioral intervention, risk stratification, and digital follow-up into structured screening pathways, endoscopic programs can evolve into multidimensional prevention platforms that reduce long-term cancer risk and improve population-level cancer control.
Citation	Shi J, Shi YD, Chen YH. Reframing endoscopic screening in upper gastrointestinal cancers: From early detection to precision primary prevention. World J Gastrointest Oncol 2026; In press

Received	2026-02-24 01:10
Peer-Review Started	2026-02-24 01:14
First Decision by Editorial Office Director	2026-03-02 08:42
Return for Revision	2026-03-02 08:42
Revised	2026-03-02 15:14
Publication Fee Transferred
Second Decision by Editor	2026-03-24 02:50
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-24 08:26
Articles in Press	2026-03-24 08:26
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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