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Articles in Press
5/28/2026 5:59:28 AM | Browse: 2 | Download: 0
| Category |
Psychiatry |
| Manuscript Type |
Observational Study |
| Article Title |
Assessment of nerve growth factor levels and clinical indicators for outcome prediction in first-episode schizophrenia
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wen-Huan Xiao, Mo-Lan Wang, Kuan-Yu Chen, Dou-Dou Yu, Ya-Qin Zhao and Jin-Rong Sun |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Yangzhou City Basic Research Program (Joint Special Project) - Health and Wellness Category |
2023-2-36, 2023-4-24, 2024-3-31, 2025-2-21 |
| Scientific Research Project of Wutaishan Hospital of Yangzhou, Jiangsu Province |
WTS2025001, WTS2025003 |
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| Corresponding Author |
Jin-Rong Sun, Department of Psychiatry, Affiliated Wutaishan Hospital of Medical College of Yangzhou University, No. 2 Wutaishan Road, Yangzhou 225003, Jiangsu Province, China. 1723487395@qq.com |
| Key Words |
Nerve growth factor; Schizophrenia; First-episode schizophrenia; Treatment outcome; Biomarker |
| Core Tip |
This study in first-episode schizophrenia found that baseline serum nerve growth factor (NGF) levels were significantly lower than in healthy controls and increased after 8 weeks of antipsychotic treatment. Baseline NGF, NGF at week 2, early NGF changes, and early psychopathological improvement each independently predicted treatment response. Combining all four indicators yielded superior predictive performance over any single measure, suggesting that dynamic NGF monitoring may assist early clinical decision-making. |
| Citation |
Xiao WH, Wang ML, Chen KY, Yu DD, Zhao YQ, Sun JR. Assessment of nerve growth factor levels and clinical indicators for outcome prediction in first-episode schizophrenia. World J Psychiatry 2026; In press |
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Received |
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2026-02-26 02:02 |
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Peer-Review Started |
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2026-02-26 02:02 |
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First Decision by Editorial Office Director |
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2026-03-20 10:00 |
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Return for Revision |
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2026-03-20 10:00 |
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Revised |
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2026-04-01 17:13 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2026-05-28 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-05-28 05:59 |
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Articles in Press |
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2026-05-28 05:59 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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