Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	120332
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Liquid biopsies in colorectal cancer screening and diagnosis
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao-Zhe Bai, Sa-ChuLa Bao, Xu-Qian Zhang and Zhen-Ni Yang
Funding Agency and Grant Number	Funding Agency Grant Number the Science and Technology Program of the Joint Fund of Scientific Research for the Public Hospitals of Inner Mongolia Academy of Medical Sciences, No. 2023GLLH0449 No. 2023GLLH0449 the Xing’an League Science and Technology Plan Project No. MBJH2024001
Corresponding Author	Zhen-Ni Yang, Associate Chief Physician, Department of Gastroenterology and Hepatology, Xing’an League People’s Hospital, No. 66 Hanshan Road, Ulanhot 137400, China. zhenniyang1107@163.com
Key Words	Colorectal cancer; Liquid biopsies; Screening; Diagnosis; Biomarkers
Core Tip	Liquid biopsy is revolutionizing colorectal cancer management by enabling noninvasive, real-time tumor profiling through analysis of circulating biomarkers. Emerging evidence supports the clinical utility of multi-analyte panels integrating circulating tumor DNA, circulating tumor cells, tumor-educated platelets, and exosomal RNAs for early detection and molecular characterization, potentially overcoming the limitations of traditional methods and guiding personalized treatment strategies.
Citation	Bai XZ, Bao SCL, Zhang XQ, Yang ZN. Liquid biopsies in colorectal cancer screening and diagnosis. World J Gastrointest Oncol 2026; In press

Received	2026-02-24 01:48
Peer-Review Started	2026-02-24 01:49
First Decision by Editorial Office Director	2026-03-13 08:06
Return for Revision	2026-03-13 08:06
Revised	2026-03-31 11:26
Publication Fee Transferred
Second Decision by Editor	2026-06-01 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-02 06:36
Articles in Press	2026-06-02 06:36
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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