Publication Name	World Journal of Critical Care Medicine
Manuscript ID	120336
Country	Japan

Category	Critical Care Medicine
Manuscript Type	Case Report
Article Title	Paroxysmal supraventricular tachycardia associated with dexmedetomidine withdrawal in an adult liver transplant recipient: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Karen Kimura, Shinichi Kai and Moritoki Egi
Funding Agency and Grant Number
Corresponding Author	Shinichi Kai, MD, PhD, Department of Anesthesia, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto, Kyoto 606-8507, Kyoto, Japan. s.kai0627@gmail.com
Key Words	Paroxysmal supraventricular tachycardia; Dexmedetomidine withdrawal; Intensive care unit; Case report
Core Tip	Dexmedetomidine withdrawal in adults is often underrecognized owing to the absence of standardized diagnostic criteria. Although most reports have described hypertension and sinus tachycardia, this case demonstrates paroxysmal supraventricular tachycardia as a potentially severe manifestation. The arrhythmia was refractory to conventional antiarrhythmic therapy, including adenosine triphosphate and β-adrenergic antagonists, but resolved rapidly after dexmedetomidine reinitiation. Clinicians should carefully review medication timelines in unexplained intensive care unit arrhythmias and avoid abrupt discontinuation after prolonged high-dose dexmedetomidine infusion.
Citation	Kimura K, Kai S, Egi M. Paroxysmal supraventricular tachycardia associated with dexmedetomidine withdrawal in an adult liver transplant recipient: A case report. World J Crit Care Med 2026; In press

Received	2026-02-25 01:36
Peer-Review Started	2026-02-25 01:41
First Decision by Editorial Office Director	2026-03-04 09:04
Return for Revision	2026-03-04 09:04
Revised	2026-03-12 05:54
Publication Fee Transferred	2026-03-16 05:43
Second Decision by Editor	2026-03-25 02:34
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-25 06:46
Articles in Press	2026-03-25 06:46
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3141(online)
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