Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	120404
DOI	10.4240/wjgs.120404
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Analgesic efficacy of thoracic paravertebral block in elderly gastric cancer patients and its impact on homeostasis
Manuscript Source	Unsolicited Manuscript
All Author List	Wan-Min Pei, Yan Ye, Jian Liu, Hui-Ling Tan, Yi-Xun Tang and Ji-Tong Liu
Funding Agency and Grant Number
Corresponding Author	Ji-Tong Liu, PhD, Department of Anesthesiology, Hunan Provincial People’s Hospital (The First Affiliated Hospital of Hunan Normal University), No. 61 Jiefang West Road, Furong District, Changsha 410005, Hunan Province, China. liujitong999@163.com
Key Words	Thoracic paravertebral block; Radical gastrectomy for gastric cancer; Postoperative analgesia; Inflammatory factors; Liver and kidney function
Core Tip	In elderly patients undergoing laparoscopic radical gastrectomy for gastric cancer, the combination of thoracic paravertebral block and general anesthesia provides superior postoperative analgesia, as evidenced by significantly lower visual analog scale scores at 6, 24, and 48 hours. This approach also effectively mitigates the inflammatory response (lower white blood cell, neutrophil percentage, and interleukin-6), improves physiological homeostasis (lower partial pressure of CO2 and blood lactate), and reduces the incidence of postoperative nausea and vomiting and overall complications. Multiple linear regression identifies the anesthesia method as the sole independent factor for postoperative pain, while the combination shows no significant additional impact on liver and kidney function.
Citation	Pei WM, Ye Y, Liu J, Tan HL, Tang YX, Liu JT. Analgesic efficacy of thoracic paravertebral block in elderly gastric cancer patients and its impact on homeostasis. World J Gastrointest Surg 2026; In press DOI: https://doi.org/10.4240/wjgs.120404
PDF	120404-in-press.pdf

Received	2026-03-25 10:15
Peer-Review Started	2026-03-25 10:15
First Decision by Editorial Office Director	2026-04-15 07:28
Return for Revision	2026-04-15 07:28
Revised	2026-05-10 09:03
Publication Fee Transferred	2026-05-15 04:40
Second Decision by Editor	2026-06-16 02:33
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-16 07:15
Articles in Press	2026-06-16 07:15
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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