Publication Name	World Journal of Gastroenterology
Manuscript ID	120447
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy
Manuscript Source	Unsolicited Manuscript
All Author List	Yong-Cheng Li, Di Pan, Hao-Nan Liu, Zi-Cheng Pei, Yu-Qi Li, Zheng-Xiang Han and Wen-Lou Liu
Funding Agency and Grant Number
Corresponding Author	Wen-Lou Liu, MD, PhD, Department of Oncology, The Affiliated Hospital of Xuzhou Medical University, No. 99 Kunpeng Road, Xuzhou Economic and Technological Development Zone, Xuzhou, Jiangsu, China, Xuzhou 221000, Jiangsu Province, China. liuwenlou@163.com
Key Words	Gastric cancer; Cytokines; Immunotherapy; Efficacy; Sintilimab; Overall survival; Interleukins
Core Tip	This study explores advanced gastric cancer (AGC) patients receiving first-line sintilimab plus chemotherapy, identifying baseline interleukin (IL)-6, IL-10, IL-17 and programmed death-ligand 1 as independent overall survival prognostic factors. A well-validated nomogram model is established, and these peripheral blood indices serve as novel biomarkers for screening AGC patients who benefit from immunotherapy.
Citation	Li YC, Pan D, Liu HN, Pei ZC, Li YQ, Han ZX, Liu WL. Baseline cytokines and programmed death-ligand 1 prognostic value in advanced gastric cancer with sintilimab plus chemotherapy. World J Gastroenterol 2026; In press

Received	2026-02-27 03:11
Peer-Review Started	2026-02-27 03:11
First Decision by Editorial Office Director	2026-03-20 11:25
Return for Revision	2026-03-20 11:25
Revised	2026-03-31 17:18
Publication Fee Transferred
Second Decision by Editor	2026-04-21 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-21 06:29
Articles in Press	2026-04-21 06:29
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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