Publication Name	World Journal of Stem Cells
Manuscript ID	120502
Country	China

Category	Allergy
Manuscript Type	Minireviews
Article Title	Extracellular vesicles in allergic rhinitis: Immune regulatory mechanisms and therapeutic applications
Manuscript Source	Unsolicited Manuscript
All Author List	Hao Fang, Jia-Ping Wang and Bing-Bing Li
Funding Agency and Grant Number
Corresponding Author	Jia-Ping Wang, Research Fellow, Department of Pediatrics, Shaoxing Central Hospital, Affiliated Central Hospital of Shaoxing University, No. 1 Huayu Road, Keqiao District, Shaoxing 312030, Zhejiang Province, China. w2846a@163.com
Key Words	Allergic rhinitis; Extracellular vesicles; Exosomes; Mesenchymal stem cells; Immune regulation; Biomarkers; Nasal mucosal barrier; Treatment strategies
Core Tip	Extracellular vesicles (EVs) exert dual roles in allergic rhinitis, with immune cell-derived EVs exacerbating inflammation and mesenchymal stem cell-derived EVs regulating immunity and repairing nasal barriers. EVs act as multi-dimensional allergic rhinitis biomarkers, and mesenchymal stem cell-derived EV-based strategies, including sustained-release delivery and cargo loading, show promising therapeutic potential, despite clinical translation challenges needing resolution.
Citation	Fang H, Wang JP, Li BB. Extracellular vesicles in allergic rhinitis: Immune regulatory mechanisms and therapeutic applications. World J Stem Cells 2026; In press

Received	2026-02-28 01:57
Peer-Review Started	2026-02-28 01:57
First Decision by Editorial Office Director	2026-03-05 09:29
Return for Revision	2026-03-05 09:29
Revised	2026-03-12 14:03
Publication Fee Transferred	2026-03-16 13:47
Second Decision by Editor	2026-04-01 02:49
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-08 10:14
Articles in Press	2026-04-08 10:14
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-0210 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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