Publication Name	World Journal of Psychiatry
Manuscript ID	120517
DOI	10.5498/wjp.120517
Country	China

Category	Psychology
Manuscript Type	Retrospective Study
Article Title	Predictive factors for post-cerebral infarction depression: A retrospective study of 156 patients
Manuscript Source	Unsolicited Manuscript
All Author List	Jia-Yi Yang, Bo-Hong Hu, Fang-Zheng Liu and Yan-Xia Gao
Funding Agency and Grant Number
Corresponding Author	Yan-Xia Gao, Department of Nursing, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), No. 818 Renmin Road, Changde 415000, Hunan Province, China. 18569106000@163.com
Key Words	Cerebral infarction; Post-stroke depression; Predictive factors; Brain-derived neurotrophic factor; Neuroinflammation; Risk model
Core Tip	Post-stroke depression (PSD) is a common and disabling complication after cerebral infarction, but early prediction of PSD remains challenging. In this cohort of 156 patients, we demonstrated clinical, neuroimaging and biological predictors most notably low serum brain-derived neurotrophic factor and high interleukin-6 levels which independently predict PSD at three months. A combination predictive model showed high diagnostic accuracy. These findings support early multidimensional risk stratification and indicate that easily measurable biomarkers can aid the screening of PSD and improve targeted early treatment in high-risk stroke survivors.
Citation	Yang JY, Hu BH, Liu FZ, Gao YX. Predictive factors for post-cerebral infarction depression: A retrospective study of 156 patients. World J Psychiatry 2026; In press DOI: https://doi.org/10.5498/wjp.120517
PDF	120517-in-press.pdf

Received	2026-04-08 09:50
Peer-Review Started	2026-04-08 09:50
First Decision by Editorial Office Director	2026-04-29 08:59
Return for Revision	2026-04-29 08:59
Revised	2026-06-01 09:30
Publication Fee Transferred	2026-06-03 02:52
Second Decision by Editor	2026-06-23 02:18
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-23 03:05
Articles in Press	2026-06-23 03:05
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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