Publication Name	World Journal of Psychiatry
Manuscript ID	120545
Country	Italy

Category	Psychiatry
Manuscript Type	Review
Article Title	Double burden of cancer and bipolar disorder: Implications for mental health care
Manuscript Source	Invited Manuscript
All Author List	Giuseppe Marano, Antonio Sottile, Oksana Di Giacomi, Marco Lanzetta, Camilla Scialpi, Francesco Pavese, Valentina Ricozzi, Silvia Rotondaro, Antonella Migliore, Tatiana D’Angelo, Paola Fuso, Gianluca Franceschini, Ida Paris and Marianna Mazza
Funding Agency and Grant Number
Corresponding Author	Marianna Mazza, Assistant Professor, MD, PhD, Department of Neurosciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo A Gemelli 8, Rome 00168, Italy. mariannamazza@hotmail.com
Key Words	Cancer; Bipolar disorder; Inflammation; Psychological factors; Mental health; Psycho-oncology
Core Tip	Patients with bipolar disorder represent a clinically vulnerable population in oncology, facing increased cancer risk, delayed diagnosis, and a high likelihood of mood destabilization during cancer treatment. This review highlights how shared inflammatory and neuroendocrine pathways, together with corticosteroid exposure and complex drug-drug interactions, may worsen both psychiatric and oncological outcomes. Recognizing bipolar disorder as a relevant modifier of cancer care is essential to promote early screening, individualized pharmacological strategies, and integrated psychiatry-oncology collaboration aimed at improving survival and quality of life.
Citation	Marano G, Sottile A, Di Giacomi O, Lanzetta M, Scialpi C, Pavese F, Ricozzi V, Rotondaro S, Migliore A, D’Angelo T, Fuso P, Franceschini G, Paris I, Mazza M. Double burden of cancer and bipolar disorder: Implications for mental health care. World J Psychiatry 2026; In press

Received	2026-03-01 09:11
Peer-Review Started	2026-03-01 09:13
First Decision by Editorial Office Director	2026-03-06 08:59
Return for Revision	2026-03-06 08:59
Revised	2026-03-11 08:35
Publication Fee Transferred
Second Decision by Editor	2026-03-30 02:31
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-03-30 09:07
Articles in Press	2026-03-30 09:07
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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