Publication Name	World Journal of Gastroenterology
Manuscript ID	120546
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Endoscopic ultrasound-guided gastrointestinal anastomosis: Evolving applications in advanced therapeutic endoscopy
Manuscript Source	Invited Manuscript
All Author List	Akrum Saleh, Ahmad Yessin, Wailea Salva, Mina Batarseh, Mandy El Khoury and Fredy Nehme
Funding Agency and Grant Number
Corresponding Author	Fredy Nehme, Assistant Professor, MD, Department of Gastroenterology and Hepatology, Indiana University School of Medicine, 340 W 10th Street, Indianapolis, IN 46202, United States. nehme.fredy@gmail.com
Key Words	Endoscopic ultrasound-guided gastrointestinal anastomosis; Lumen-apposing metal stent; Therapeutic endoscopic ultrasound; Gastric outlet obstruction; Postsurgical anatomy; Afferent loop syndrome
Core Tip	Endoscopic ultrasound (EUS)-guided gastrointestinal anastomosis has emerged as a highly effective minimally invasive platform for managing complex obstructive and altered anatomy conditions, including malignant gastric outlet obstruction, endoscopic retrograde cholangiopancreatography (ERCP) in Roux-en-Y gastric bypass, and afferent loop syndrome. Recent randomized data support EUS-guided gastroenterostomy as an effective alternative to surgical bypass and duodenal stenting. EUS-directed transgastric ERCP demonstrates comparable technical success to laparoscopy-assisted ERCP with shorter procedural times. As device technology and standardization improve, EUS-guided gastrointestinal anastomosis is poised to become an integral component of advanced therapeutic endoscopy.
Citation	Saleh A, Yessin A, Salva W, Batarseh M, El Khoury M, Nehme F. Endoscopic ultrasound-guided gastrointestinal anastomosis: Evolving applications in advanced therapeutic endoscopy. World J Gastroenterol 2026; In press

Received	2026-03-01 09:20
Peer-Review Started	2026-03-01 09:20
First Decision by Editorial Office Director	2026-04-03 07:57
Return for Revision	2026-04-03 07:57
Revised	2026-05-01 23:19
Publication Fee Transferred
Second Decision by Editor	2026-05-20 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-20 08:03
Articles in Press	2026-05-20 08:03
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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