Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	120569
DOI	10.4251/wjgo.120569
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Clinical and pathological features and treatment of nine cases of gastrointestinal composite gangliocytoma/neuroma and neuroendocrine tumor
Manuscript Source	Unsolicited Manuscript
All Author List	Peng-Cheng Zhang, Jing-Jie Wang, Jun Li and Ai-Qing Li
Funding Agency and Grant Number
Corresponding Author	Ai-Qing Li, Chief Physician, Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qinchun Road, Hangzhou 310003, Zhejiang Province, China. 3310015@zju.edu.cn
Key Words	Composite gangliocytoma/neuroma and neuroendocrine tumor; Clinicopathological features; Endoscopic therapy; Immunohistochemistry; Prognosis
Core Tip	Composite gangliocytoma/neuroma and neuroendocrine tumor (CoGNET) is an extremely rare neuroendocrine neoplasm. This study reports the largest case series of gastrointestinal CoGNET in China to date, including the world’s first reported case of primary rectal CoGNET as we know. We systematically analyzed the clinicopathological, endoscopic, and radiological characteristics of 9 pathologically confirmed CoGNET cases. Our findings validated the safety and long-term efficacy of endoscopic resection, and confirmed an excellent prognosis for all patients, including the case with lymph node metastasis. This work provides pivotal real-world evidence to optimize clinical diagnosis and treatment strategies for this rare disease.
Citation	Zhang PC, Wang JJ, Li J, Li AQ. Clinical and pathological features and treatment of nine cases of gastrointestinal composite gangliocytoma/neuroma and neuroendocrine tumor. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.120569
PDF	120569-in-press.pdf

Received	2026-03-03 03:03
Peer-Review Started	2026-03-03 03:07
First Decision by Editorial Office Director	2026-03-09 09:17
Return for Revision	2026-03-11 12:33
Revised	2026-03-30 15:29
Publication Fee Transferred	2026-04-04 15:03
Second Decision by Editor	2026-06-08 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-08 10:25
Articles in Press	2026-06-08 10:25
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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