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Publication Name World Journal of Transplantation
Manuscript ID 120572
Country United Kingdom
Category Transplantation
Manuscript Type Minireviews
Article Title Redefining weight management after liver transplantation with glucagon-like peptide one and gastric inhibitory polypeptide receptor agonists
Manuscript Source Invited Manuscript
All Author List Soha Elatrebi, Rowan Abuyadek, Sohaila Mohamed Mohamed Abdelbar, Muhammad S Ahmad, Mohamed Ayyad, Muhammad AbdelAziz Quoritem, Rodaina Osama Abdel Majid, Manar Arafat, Ahmed Amgad and Amr Alnagar
Funding Agency and Grant Number
Corresponding Author Amr Alnagar, PhD, Department of General Surgery, University Hospitals of Birmingham, 6 Chamberlain Road, Birmingham B9 5SS, United Kingdom. amr.alnagar@nhs.net
Key Words Liver transplantation; Obesity; Metabolic syndrome; Steatosis; Weight loss
Core Tip While liver transplantation can be life-saving for end-stage liver diseases, it can exacerbate metabolic issues due to underlying pathology and immunosuppressive regimens. A thorough management plan is essential to prevent complications like metabolic dysfunction-associated steatotic liver disease, chronic renal dysfunction, and diabetes, ultimately improving prognosis and quality of life. glucagon-like peptide-1 (GLP-1) and GLP-1/glucose-dependent insulinotropic polypeptide receptor agonists have gained United States Food and Drug Administration approval for long-term weight management, but their long-term safety, optimal dosing, and effectiveness in transplant recipients remain underexplored. This review addresses the pathophysiology, risk factors, and burden of metabolic complications in liver transplant recipients while evaluating the potential role of GLP-1 and GLP-1/glucose-dependent insulinotropic polypeptide receptor agonists for managing these issues.
Citation Elatrebi S, Abuyadek R, Abdelbar SMM, Ahmad MS, Ayyad M, Quoritem MA, Abdel Majid RO, Arafat M, Amgad A, Alnagar A. Redefining weight management after liver transplantation with glucagon-like peptide one and gastric inhibitory polypeptide receptor agonists. World J Transplant 2026; In press
Received
2026-03-02 03:33
Peer-Review Started
2026-03-02 03:34
First Decision by Editorial Office Director
2026-03-04 08:59
Return for Revision
2026-03-04 08:59
Revised
2026-03-18 07:00
Publication Fee Transferred
Second Decision by Editor
2026-05-19 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-05-19 11:42
Articles in Press
2026-05-19 11:42
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com