Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	120628
Country	China

Category	Surgery
Manuscript Type	Clinical Trials Study
Article Title	Safety of opening wounds after cold resection of colorectal cancer patients’ intestinal polyps ten mm or larger
Manuscript Source	Unsolicited Manuscript
All Author List	Lin-Da Li, Zhang-Han Chen, Yun-Shi Zhong, Dong-Li He, De-Xiang Zhu, Jian-Min Xu and Jia-Chen Jing
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China No. 82273025 and No. 82403010
Corresponding Author	Jia-Chen Jing, Endoscopy Center, Shanghai Xuhui Central Hospital, No. 366, Longchuan North Road, Shanghai 200030, China. jingjiachen2025@126.com
Key Words	Colorectal cancer patients; Colonic polyps; Rectal polyps; Post-polypectomy bleeding; Cold snare polypectomy; Metal clips
Core Tip	The routine use of prophylactic hemoclips following cold snare polypectomy for colorectal polyps ≥ 10 mm does not reduce the risk of bleeding but is associated with increased operative time and cost. This study, utilizing advanced statistical methods (inverse probability of treatment weighting, Firth regression, etc.), suggests that a non-clipping strategy yields comparable safety outcomes while potentially enhancing procedural efficiency and cost-effectiveness, challenging a common clinical practice.
Citation	Li LD, Chen ZH, Zhong YS, He DL, Zhu DX, Xu JM, Jing JC. Safety of opening wounds after cold resection of colorectal cancer patients’ intestinal polyps ten mm or larger. World J Gastrointest Endosc 2026; In press

Received	2026-03-04 03:13
Peer-Review Started	2026-03-04 03:14
First Decision by Editorial Office Director	2026-03-12 09:05
Return for Revision	2026-03-12 16:01
Revised	2026-04-02 22:05
Publication Fee Transferred	2026-04-08 03:38
Second Decision by Editor	2026-04-29 02:57
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-29 07:49
Articles in Press	2026-04-29 07:49
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5190 (online)
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