Publication Name	World Journal of Gastroenterology
Manuscript ID	120735
DOI	10.3748/wjg.120735
Country	Philippines

Category	Gastroenterology & Hepatology
Manuscript Type	Correspondence
Article Title	Letter to the Editor: Adjunctive low-dose flupentixol-melitracen with lansoprazole rapidly improves functional dyspepsia - implications from a randomized, double-blind trial
Manuscript Source	Invited Manuscript
All Author List	Snehasis Nayak
Funding Agency and Grant Number
Corresponding Author	Snehasis Nayak, Department of Student Research Committee, University of Visayas Gullas College of Medicine, Banilad, Cebu 6000, Philippines. snehasisnayak37@gmail.com
Key Words	Functional dyspepsia; Lansoprazole; Flupentixol; Melitracen; Prokinetics; Rome IV
Core Tip	Combining lansoprazole (30 mg daily) with low-dose flupentixol-melitracen can effectively address both the symptoms and psychosocial factors of functional dyspepsia. This commentary discusses the potential role of early gut-brain axis modulation, examines the strengths and limitations of current evidence, highlights regulatory and geographic differences in the use of flupentixol-melitracen, and emphasizes the need for large multicenter studies to identify patients most likely to benefit from this therapeutic approach.
Citation	Nayak S. Letter to the Editor: Adjunctive low-dose flupentixol-melitracen with lansoprazole rapidly improves functional dyspepsia - implications from a randomized, double-blind trial. World J Gastroenterol 2026; In press DOI: https://doi.org/10.3748/wjg.120735
PDF	120735-in-press.pdf

Received	2026-03-09 07:03
Peer-Review Started	2026-03-09 07:03
First Decision by Editorial Office Director	2026-04-08 08:57
Return for Revision	2026-04-08 08:57
Revised	2026-05-15 02:58
Publication Fee Transferred
Second Decision by Editor	2026-06-24 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-24 05:53
Articles in Press	2026-06-24 05:53
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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