Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	120740
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Efficacy and adverse reactions of endoscopic submucosal dissection and endoscopic submucosal tunnel dissection in early esophageal cancer patients
Manuscript Source	Unsolicited Manuscript
All Author List	Dong Zhang, Xiu-Xian Hao, Chao Zhang and Yan Liang
Funding Agency and Grant Number
Corresponding Author	Yan Liang, Research Fellow, Department of Quality Control, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, No. 127 South Siliu Road, Qingdao 266042, Shandong Province, China. nayliang@163.com
Key Words	Endoscopic submucosal dissection; Endoscopic submucosal tunnel dissection; Early esophageal cancer; Treatment outcome; Adverse reactions
Core Tip	This retrospective study provides comparative evidence on the use of endoscopic submucosal tunnel dissection (ESTD) vs conventional endoscopic submucosal dissection in treating early esophageal cancer. We found that ESTD is associated with a high R0 resection rate, low recurrence, and few adverse reactions. Moreover, ESTD demonstrates superior surgical efficiency (short procedure time and reduced bleeding) and attenuates postoperative inflammatory responses, which correlate with improved long-term quality of life. These results position ESTD as a potentially more effective and less traumatic minimally invasive option compared with other approaches, warranting further prospective validation.
Citation	Zhang D, Hao XX, Zhang C, Liang Y. Efficacy and adverse reactions of endoscopic submucosal dissection and endoscopic submucosal tunnel dissection in early esophageal cancer patients. World J Gastrointest Surg 2026; In press

Received	2026-03-10 00:54
Peer-Review Started	2026-03-10 00:54
First Decision by Editorial Office Director	2026-03-26 10:01
Return for Revision	2026-03-26 10:01
Revised	2026-04-15 01:49
Publication Fee Transferred	2026-04-23 02:54
Second Decision by Editor	2026-05-26 02:36
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-26 06:45
Articles in Press	2026-05-26 06:45
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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