Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	120791
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Poorly differentiated adenocarcinoma misdiagnosed as gastrointestinal stromal tumor: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Li-Ying Xu, Yu-Qi Lin, Ri-Yan Yao, Mei-Lin Yang, Hua-Feng Shen and Gao-Song Zhang
Funding Agency and Grant Number
Corresponding Author	Gao-Song Zhang, Associate Chief Physician, Department of Gastroenterology, Xinchang County People’s Hospital, No. 117 Gushan Middle Road, Shaoxing 312500, Zhejiang Province, China. gsongz@163.com
Key Words	Gastrointestinal stromal tumor; Adenocarcinoma; Endoscopic submucosal dissection; Pathology; Case report
Core Tip	Gastric adenocarcinoma with predominant submucosal growth may closely mimic gastrointestinal stromal tumor. In this case, a small submucosal tumor-like gastric lesion with surface erosion and bleeding was misdiagnosed as gastrointestinal stromal tumor because endoscopic ultrasound suggested a muscularis propria-derived lesion and diagnostic endoscopic submucosal dissection biopsy showed spindle cell-like morphology. The final diagnosis of poorly differentiated adenocarcinoma was made after surgical resection. Small submucosal tumor-like lesions with mucosal abnormalities require multimodal evaluation, adequate tissue acquisition, and timely immunohistochemical assessment to reduce misdiagnosis.
Citation	Xu LY, Lin YQ, Yao RY, Yang ML, Shen HF, Zhang GS. Poorly differentiated adenocarcinoma misdiagnosed as gastrointestinal stromal tumor: A case report. World J Gastrointest Oncol 2026; In press

Received	2026-03-09 03:06
Peer-Review Started	2026-03-09 03:07
First Decision by Editorial Office Director	2026-03-27 13:28
Return for Revision	2026-03-27 13:50
Revised	2026-04-09 16:34
Publication Fee Transferred	2026-04-13 12:07
Second Decision by Editor	2026-05-18 02:48
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-18 07:38
Articles in Press	2026-05-18 07:38
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com