Publication Name	World Journal of Translational Medicine
Manuscript ID	120845
Country	India

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Esophageal varices in pregnancy: Strategies to optimize maternal and fetal outcomes
Manuscript Source	Invited Manuscript
All Author List	Meenakshi Rajput and Adarsh kumar
Funding Agency and Grant Number
Corresponding Author	Adarsh kumar, Associate Professor, DM, MD, Department of Nephrology and Renal Transplant Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, Ansari Nagar East, Near AIIMS Metro Station, 110029, New Delhi, India. adarshnephro081@gmail.com
Key Words	Esophageal varices; Pregnancy; Portal hypertension; Variceal bleeding; Prophylaxis
Core Tip	Portal hypertension in pregnancy poses challenges due to physiological changes in blood flow, variceal progression, and the risk of liver decompensation. Preconception counseling and early risk assessment are essential, focusing on prior variceal bleeding, variceal size, thrombocytopenia, and liver disease severity. Upper gastrointestinal endoscopy should ideally be done before conception; if not, it can be safely performed in the second trimester when clinically indicated, with minimal sedation and proper maternal positioning. For primary prophylaxis, non-selective beta-blocker (NSBB) is preferred, with endoscopic variceal ligation as an alternative when NSBBs are contraindicated or not tolerated. Optimal care requires a multidisciplinary team in a specialized center. Current hepatology guidelines provide limited pregnancy-specific recommendations; this review consolidates the available evidence with existing clinical experience in managing portal hypertension during pregnancy.
Citation	Rajput M, Kumar A. Esophageal varices in pregnancy: Strategies to optimize maternal and fetal outcomes. World J Transl Med 2026; In press

Received	2026-03-10 00:33
Peer-Review Started	2026-03-10 00:33
First Decision by Editorial Office Director	2026-06-05 06:20
Return for Revision	2026-06-05 23:14
Revised	2026-06-16 17:02
Publication Fee Transferred
Second Decision by Editor	2026-07-07 02:57
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-07 06:06
Articles in Press	2026-07-07 06:06
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-6132 (online)
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