Publication Name	World Journal of Cardiology
Manuscript ID	120973
DOI	10.4330/wjc.120973
Country	United States

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	High-power short-duration radiofrequency ablation for atrial fibrillation: There is still a country for “old men”
Manuscript Source	Invited Manuscript
All Author List	Andrea Giuseppe Porto, Paolo Zappulla, Giuseppe Sgarito and Sergio Conti
Funding Agency and Grant Number
Corresponding Author	Sergio Conti, Division of Cardiology, Department of Internal Medicine, Section of Cardiac Electrophysiology, University of Iowa Health Care Center, 200 Hawkins Dr, Iowa City, IA 52242, United States. sergioconti.md@gmail.com
Key Words	High-power short-duration; Atrial fibrillation; Catheter ablation; Radiofrequency; Lesion formation; Biophysics; Pulsed field ablation
Core Tip	High-power short-duration (HPSD) is the latest development in radiofrequency (RF) catheter ablation. HPSD has redefined the RF ablation landscape, offering proven advantages over low-power long-duration RF ablation in both safety and efficacy. However, there are still safety issues related to RF thermal effects. In addition, even when following standardized protocols, HPSD RF ablation remains operator-dependent. Pulsed field ablation (PFA) is an innovative, non-thermal ablation technique that employs pulsed electric fields to ablate myocardial tissue selectively, sparing adjacent non-cardiac structures. PFA seems more reproducible, reducing procedural time while maintaining non-inferior efficacy. In the era of PFA, HPSD RF ablation should therefore be viewed not as a technology being replaced, but rather as a mature and efficient strategy that will likely coexist with emerging non-thermal ablation modalities.
Citation	Porto AG, Zappulla P, Sgarito G, Conti S. High-power short-duration radiofrequency ablation for atrial fibrillation: There is still a country for “old men”. World J Cardiol 2026; In press DOI: https://doi.org/10.4330/wjc.120973
PDF	120973-in-press.pdf

Received	2026-03-12 03:24
Peer-Review Started	2026-03-12 03:26
First Decision by Editorial Office Director	2026-05-29 09:02
Return for Revision	2026-05-29 09:02
Revised	2026-06-18 12:14
Publication Fee Transferred
Second Decision by Editor	2026-06-30 02:42
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-30 03:24
Articles in Press	2026-06-30 03:24
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8462 (online)
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