Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	120982
Country	Taiwan

Category	Oncology
Manuscript Type	Case Report
Article Title	Long-term complete response in stage IVa esophageal squamous cell carcinoma treated with chemoradiotherapy and modulated electro-hyperthermia: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Chih-Wu Cheng, Wen-Tyng Li, Yu-Ting Lee, Kam-Hong Kam and Yuk-Wah Tsang
Funding Agency and Grant Number	Funding Agency Grant Number the Research Program of Ditmanson Medical Foundation Chia-Yi Christian Hospital R112-017
Corresponding Author	Wen-Tyng Li, Associate Professor, PhD, Department of Biomedical Engineering, Chung Yuan Christian University, No. 200 Zhongbei Road, Zhongli District, Taoyuan 320314, Taiwan. wtli@cycu.edu.tw
Key Words	Esophageal squamous cell carcinoma; Chemoradiotherapy; Modulated electro-hyperthermia; Cachexia; Long-term complete response; Case report
Core Tip	This case report describes a patient with stage IVa esophageal squamous cell carcinoma complicated by severe cachexia, pneumonia, and anemia who achieved durable complete remission exceeding five years after definitive chemoradiotherapy combined with adjunctive electrohyperthermia. Despite multiple poor prognostic factors, aggressive multimodal therapy together with early intensive supportive care enabled successful treatment completion and long-term disease control. This case highlights the potential role of electrohyperthermia as an adjunct to chemoradiotherapy in improving outcomes in selected high-risk patients with advanced esophageal cancer with histopathological confirmation of complete response.
Citation	Cheng CW, Li WT, Lee YT, Kam KH, Tsang YW. Long-term complete response in stage IVa esophageal squamous cell carcinoma treated with chemoradiotherapy and modulated electro-hyperthermia: A case report. World J Gastrointest Oncol 2026; In press

Received	2026-03-16 02:08
Peer-Review Started	2026-03-16 02:10
First Decision by Editorial Office Director	2026-03-20 10:09
Return for Revision	2026-03-20 10:09
Revised	2026-04-01 11:30
Publication Fee Transferred
Second Decision by Editor	2026-05-19 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-19 06:49
Articles in Press	2026-05-19 06:49
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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