Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	120985
Country	China

Category	Oncology
Manuscript Type	Observational Study
Article Title	Association of uterine artery Doppler, follicle-stimulating hormone, and anti-Müllerian hormone with post-chemotherapy ovarian reserve in reproductive-age colorectal cancer patients
Manuscript Source	Unsolicited Manuscript
All Author List	Chun-Ya Chen, Lin-Ling Tan, Jun-Yi Zhang and Ya-Ping Zhang
Funding Agency and Grant Number
Corresponding Author	Ya-Ping Zhang, Associate Chief Physician, Department of Oncology, The Affiliated Xiaoshan Hospital, Hangzhou Normal University, No. 728 Yucai North Road, Xiaoshan District, Hangzhou 311200, Zhejiang Province, China. fuyou_chun2025@163.com
Key Words	Colorectal neoplasms; Ovarian reserve function; Ultrasonography; Blood flow parameters; Follicle-stimulating hormone; Anti-Müllerian hormone; Women
Core Tip	Combined assessment of uterine artery Doppler parameters [pulsatility index (PI), resistance index (RI), and peak systolic velocity (PSV)] with serum follicle-stimulating hormone (FSH) and anti-Müllerian hormone (AMH) levels demonstrates superior predictive value for diminished ovarian reserve in reproductive-aged colorectal cancer patients after chemotherapy. The combined detection achieved an area under the curve of 0.950, significantly outperforming any single indicator, with PI, RI, and FSH positively correlated, while PSV and AMH negatively correlated with ovarian reserve decline. This multimodal approach provides a non-invasive, comprehensive strategy for early identification of chemotherapy-induced ovarian damage.
Citation	Chen CY, Tan LL, Zhang JY, Zhang YP. Association of uterine artery Doppler, follicle-stimulating hormone, and anti-Müllerian hormone with post-chemotherapy ovarian reserve in reproductive-age colorectal cancer patients. World J Gastrointest Oncol 2026; In press

Received	2026-03-17 10:07
Peer-Review Started	2026-03-17 10:07
First Decision by Editorial Office Director	2026-03-26 09:40
Return for Revision	2026-03-26 09:40
Revised	2026-03-30 10:50
Publication Fee Transferred	2026-04-02 05:37
Second Decision by Editor	2026-05-07 03:22
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-07 09:23
Articles in Press	2026-05-07 09:23
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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