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Publication Name World Journal of Transplantation
Manuscript ID 120986
DOI 10.5500/wjt.120986
Country China
Category Transplantation
Manuscript Type Evidence Review
Article Title Research advances in postoperative growth and development following paediatric kidney transplantation: Mechanisms, influencing factors and clinical management
Manuscript Source Invited Manuscript
All Author List Yu-Yang Wang, Gai Hang, Quan Wen, Yun-Peng Guo, Chen Long and Bo Chen
Funding Agency and Grant Number
Corresponding Author Bo Chen, Department of Urinary Surgery, Tongliao People's Hospital, No. 668 Horqin Street, Horqin District, Tongliao 028000, Inner Mongolia Autonomous Region, China. chenmuxin@126.com
Key Words Paediatric kidney transplantation; Growth and development; Growth hormone; Immunosuppression; Graft function; Narrative review
Core Tip Paediatric kidney transplantation markedly improves survival in children with end-stage kidney disease, yet post-transplant growth and developmental impairment remain a major challenge. This review highlights the multifactorial mechanisms underlying poor growth after paediatric kidney transplantation, including immunosuppressive exposure, incomplete renal recovery, nutritional deficits, and transplant-related complications. It further summarises emerging predictive models and personalised interventions, emphasising early transplantation, steroid-sparing or optimised immunosuppressive strategies, and careful use of growth hormone as key approaches to improve long-term growth and developmental outcomes.
Citation Wang YY, Hang G, Wen Q, Guo YP, Long C, Chen B. Research advances in postoperative growth and development following paediatric kidney transplantation: Mechanisms, influencing factors and clinical management. World J Transplant 2026; In press
PDF 120986-in-press.pdf
Received
2026-03-13 02:46
Peer-Review Started
2026-03-13 02:47
First Decision by Editorial Office Director
2026-04-03 07:31
Return for Revision
2026-04-03 07:31
Revised
2026-05-20 09:24
Publication Fee Transferred
Second Decision by Editor
2026-08-10 02:45
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-08-10 10:02
Articles in Press
2026-08-10 10:02
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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