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Articles in Press
9/4/2026 9:05:46 AM | Browse: 7 | Download: 0
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Risk factors for anastomotic leakage after radical colorectal cancer surgery and its impact on prognosis: Clinical education research
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu Wang, Tao Wang, Zhi-Duan Xu, Su-Hang Wang and Fang-Fang Chen |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Teaching Research Project of Bengbu Medical University, Anhui Province (Key Project) |
No. 2025fyjyxm10 |
| Scientific Research Project of Anhui Higher Education Institutions |
No. 2024AH051186 |
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| Corresponding Author |
Yu Wang, Chief Physician, The Four Branches of General Surgery, The First Affiliated Hospital of Bengbu Medical University, No. 287 Changhuai Road, Bengbu 233000, Anhui Province, China. house2737@163.com |
| Key Words |
Colorectal cancer; Radical surgery; Anastomotic leakage; Risk factors; Prognosis; Retrospective cohort study; Action-Process-Object-Schema theory; Critical thinking |
| Core Tip |
This retrospective cohort study evaluated the incidence, risk factors, and prognostic impact of anastomotic leakage (AL) after radical colorectal cancer surgery. Among 200 patients, AL occurred in 11.0% and was independently associated with body mass index ≥ 25 kg/m², diabetes mellitus, rectal tumor location, neoadjuvant therapy, hypoalbuminemia, prolonged operation time, and increased intraoperative blood loss, while protective stoma was a significant protective factor. Patients with AL had significantly worse short-term outcomes, including higher complication and reoperation rates, prolonged hospitalization, and delayed adjuvant chemotherapy. Importantly, AL was also associated with inferior long-term survival and was identified as an independent predictor of poorer disease-free survival. |
| Citation |
Wang Y, Wang T, Xu ZD, Wang SH, Chen FF. Risk factors for anastomotic leakage after radical colorectal cancer surgery and its impact on prognosis: Clinical education research. World J Gastrointest Surg 2026; In press
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| PDF |
121006-in-press.pdf
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Received |
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2026-04-28 12:15 |
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Peer-Review Started |
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2026-04-28 12:15 |
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First Decision by Editorial Office Director |
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2026-05-22 03:08 |
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Return for Revision |
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2026-05-22 03:08 |
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Revised |
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2026-06-08 10:10 |
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Publication Fee Transferred |
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2026-06-24 01:47 |
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Second Decision by Editor |
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2026-09-02 02:54 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2026-09-04 09:05 |
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Articles in Press |
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2026-09-04 09:05 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Copyright |
©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
Copyright © 1993-2026 Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA. All rights reserved, including rights relating to text and data mining, AI training, and similar technologies. For open-access content, the applicable copyright and licensing terms govern.
