Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	121016
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Prognostic value of acute liver injury in cirrhotic patients after the transjugular intrahepatic portosystemic shunt procedure
Manuscript Source	Unsolicited Manuscript
All Author List	Liang Yin, Jing-Qiu Zhang, Yi-Jiang Zhu, Sen-Lin Chu, Kai-Cai Liu, Pan Zhang, Li Dong, Yong-Hui Zhang, Dong Lu, Wei-Fu Lv, Chun-Ze Zhou and De-Lei Cheng
Funding Agency and Grant Number	Funding Agency Grant Number 2023 Health Research Program of Anhui AHWJ2023A20508
Corresponding Author	De-Lei Cheng, PhD, Department of Interventional Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, 17 Lujiang Rd, Hefei 230000, Anhui Province, China. chengdelei@hotmail.com
Key Words	Transjugular intrahepatic portosystemic shunt; Acute liver injury; Liver cirrhosis; Hepatic encephalopathy; Prognosis; Risk factors
Core Tip	Acute liver injury (ALI) is a common and serious complication following the transjugular intrahepatic portosystemic shunt (TIPS) procedure in cirrhotic patients. This study highlights the incidence, risk factors, and prognostic implications of ALI after TIPS. Our findings demonstrate that post-TIPS ALI significantly increases the risk of overt hepatic encephalopathy and reduces overall survival. Independent predictors of mortality include sarcopenia, Model for End-Stage Liver Disease score, age, and post-TIPS ALI. A nomogram was developed based on these key factors, offering a reliable tool for survival prediction and clinical decision-making in managing cirrhotic patients undergoing TIPS.
Citation	Yin L, Zhang JQ, Zhu YJ, Chu SL, Liu KC, Zhang P, Dong L, Zhang YH, Lu D, Lv WF, Zhou CZ, Cheng DL. Prognostic value of acute liver injury in cirrhotic patients after the transjugular intrahepatic portosystemic shunt procedure. World J Gastrointest Surg 2026; In press

Received	2026-03-13 00:46
Peer-Review Started	2026-03-13 00:55
First Decision by Editorial Office Director	2026-04-16 07:27
Return for Revision	2026-04-16 07:27
Revised	2026-04-28 07:26
Publication Fee Transferred
Second Decision by Editor	2026-05-18 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-18 08:39
Articles in Press	2026-05-18 08:39
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com