Publication Name	World Journal of Clinical Cases
Manuscript ID	121062
DOI	10.12998/wjcc.121062
Country	Saudi Arabia

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Irritable bowel syndrome and colon cancer: A meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Hyder Osman Mirghani and Ghadah Osman Alanazi
Funding Agency and Grant Number
Corresponding Author	Hyder Osman Mirghani, Full Professor, MD, Internal Medicine, Faculty of Medicine, University of Tabuk, Prince Fahd Bin Sulta, Tabuk 51941, Saudi Arabia. s.hyder63@hotmail.com
Key Words	Irritable bowel syndrome; Colon cancer; Colorectal cancer; Rome criteria; Misdiagnosis; Cancer risk; Functional bowel disorders
Core Tip	Irritable bowel syndrome (IBS) is prevalent, and this prevalence varies depending on geography, diagnostic methods, and sociodemographic factors. The Rome criteria are the most commonly used diagnostic method, however, an important limitation of the Rome criteria overall is their potential overlap with organic diseases. This can complicate diagnosis and increase the risk of missing significant organic pathology if careful clinical evaluation is not performed. There is a recent concern regarding the association between IBS and colorectal cancer (CRC), particularly in those < 50 years of age. The current review synthesized the most recent evidence regarding the association between CRC and IBS.
Citation	Mirghani HO, Alanazi GO. Irritable bowel syndrome and colon cancer: A meta-analysis. World J Clin Cases 2026; In press DOI: https://doi.org/10.12998/wjcc.121062
PDF	121062-in-press.pdf

Received	2026-03-16 03:45
Peer-Review Started	2026-03-16 03:45
First Decision by Editorial Office Director	2026-04-15 08:56
Return for Revision	2026-04-15 08:56
Revised	2026-05-10 05:11
Publication Fee Transferred
Second Decision by Editor	2026-06-23 02:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-23 08:21
Articles in Press	2026-06-23 08:21
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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