Publication Name	World Journal of Gastroenterology
Manuscript ID	121090
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Complete clip closure with staged triple-lumen feeding tube reduces delayed adverse events after duodenal endoscopic submucosal dissection
Manuscript Source	Unsolicited Manuscript
All Author List	Yue Song, Jing Wang, Fan Meng and Qi Wu
Funding Agency and Grant Number	Funding Agency Grant Number Beijing Research Ward Excellence Program No. BRWEP2024W032150100 Beijing Research Ward Excellence Program No. BRWEP2024W032150112 Hygiene and Health Development Scientific Research Fostering Plan of Haidian District, Beijing No. HP2024-19-503002 Beijing Municipal Administration of Hospitals Incubating Program No. PX2024041 Application Demonstration and Promotion of Ultrasound/Confocal Endoscopy Technology in the Diagnosis and Treatment of Esophageal Tumors No. 2023YFC2413802
Corresponding Author	Qi Wu, Chief, MD, PhD, Professor, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Endoscopy Center, Peking University Cancer Hospital and Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. wuqi1973@bjmu.edu.cn
Key Words	Duodenum; Endoscopic submucosal dissection; Delayed adverse events; Mucosal defect closure; Triple-lumen feeding tube; Perioperative management
Core Tip	Delayed adverse events (AEs) remain a major challenge after duodenal endoscopic submucosal dissection (ESD). In this real-world cohort, complete clip closure and postoperative triple-lumen feeding tube management were independently associated with fewer delayed AEs, with patients receiving both measures exhibiting the lowest observed complication rate. Furthermore, triple-lumen feeding tube drainage was associated with attenuated early postoperative inflammation and improved nutritional status. These results provide practical evidence to inform perioperative management in high-risk duodenal ESD.
Citation	Song Y, Wang J, Meng F, Wu Q. Complete clip closure with staged triple-lumen feeding tube reduces delayed adverse events after duodenal endoscopic submucosal dissection. World J Gastroenterol 2026; In press

Received	2026-03-17 01:19
Peer-Review Started	2026-03-17 01:20
First Decision by Editorial Office Director	2026-03-28 03:36
Return for Revision	2026-03-28 03:36
Revised	2026-04-10 17:10
Publication Fee Transferred	2026-04-14 02:46
Second Decision by Editor	2026-04-22 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-04-22 07:15
Articles in Press	2026-04-22 07:15
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com