BPG is committed to discovery and dissemination of knowledge
Articles in Press
6/8/2026 5:30:02 AM | Browse: 6 | Download: 0
| Category |
Orthopedics |
| Manuscript Type |
Basic Study |
| Article Title |
Early oral celecoxib prevents contracture and modulates capsular fibrosis in a validated model of post-traumatic arthrofibrosis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Luis Palacios-Díaz, Blanca Diez Sánchez, Ángel González-García, Eva Manuela Pena-Burgos, José J Pozo-Kreilinger, M T Carrascal-Morillo, Alejandro Bustos, Pablo Sanchez-Urgelles, Samuel Antuña and Raul Barco |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| SECEC 17th Basic Research Grant |
|
| SECOT Ayudas a Investigación en COT 2024 |
|
|
| Corresponding Author |
Luis Palacios-Díaz, Department of Shoulder and Elbow Surgery, La Paz University Hospital, Paseo de la castellana 291, Madrid 28046, Spain. lpalaciosdiaz96@gmail.com |
| Key Words |
Post-traumatic arthrofibrosis; Joint stiffness; Celecoxib; Posterior capsular fibrosis; Rat model |
| Core Tip |
Post-traumatic arthrofibrosis remains a challenging condition with limited preventive strategies. In this rat model, celecoxib reduced capsular fibrosis and improved biomechanical outcomes, suggesting a potential disease-modifying effect on fibrotic remodeling rather than solely providing symptomatic relief. These findings support further investigation of celecoxib as a preventive intervention for post-traumatic joint contracture and provide a rationale for future translational and clinical studies. |
| Citation |
Palacios-Díaz L, Diez Sánchez B, González-García Á, Pena-Burgos EM, Pozo-Kreilinger JJ, Carrascal-Morillo MT, Bustos A, Sanchez-Urgelles P, Antuña S, Barco R. Early oral celecoxib prevents contracture and modulates capsular fibrosis in a validated model of post-traumatic arthrofibrosis. World J Orthop 2026; In press
|
| PDF |
121157-in-press.pdf
|
 |
Received |
|
2026-03-18 06:55 |
|
Peer-Review Started |
|
2026-03-18 06:58 |
|
First Decision by Editorial Office Director |
|
2026-04-04 02:50 |
|
Return for Revision |
|
2026-04-04 02:50 |
|
Revised |
|
2026-04-09 13:22 |
|
Publication Fee Transferred |
|
2026-04-24 11:12 |
|
Second Decision by Editor |
|
2026-06-08 02:40 |
 |
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2026-06-08 05:30 |
|
Articles in Press |
|
2026-06-08 05:30 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
|
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
