Publication Name	World Journal of Psychiatry
Manuscript ID	121171
DOI	10.5498/wjp.121171
Country	China

Category	Psychiatry
Manuscript Type	Minireviews
Article Title	Review of serum inflammatory markers linked to depression and sleep quality in irritable bowel syndrome patients
Manuscript Source	Unsolicited Manuscript
All Author List	Si-Yu Zhu, Yin Fu, Jia-Ze Li, Zhe Zhang, Te-Ha-Si Wang, Jun Hu and Ji Li
Funding Agency and Grant Number
Corresponding Author	Ji Li, Professor, Department of Basic Medical College, Heilongjiang University of Chinese Medicine, No. 24 Heping Road, Xiangfang District, Harbin 150040, Heilongjiang Province, China. 18346079850@163.com
Key Words	Serum inflammatory markers; Irritable bowel syndrome; Depression; Sleep quality; Correlation; Review
Core Tip	This minireview innovatively summarizes the correlation between serum inflammatory markers and the occurrence of depression and sleep disorders in patients with irritable bowel syndrome. It specifically focuses on interleukin-6, tumor necrosis factor-α, and interleukin-8, highlighting the crucial role of the gut-brain axis and systemic inflammation in this process. The review proposes that monitoring and targeting these inflammatory indicators could offer new strategies for preventing and treating these common irritable bowel syndrome comorbidities.
Citation	Zhu SY, Fu Y, Li JZ, Zhang Z, Wang THS, Hu J, Li J. Review of serum inflammatory markers linked to depression and sleep quality in irritable bowel syndrome patients. World J Psychiatry 2026; In press DOI: https://doi.org/10.5498/wjp.121171
PDF	121171-in-press.pdf

Received	2026-04-24 10:59
Peer-Review Started	2026-04-24 10:59
First Decision by Editorial Office Director	2026-05-21 03:24
Return for Revision	2026-05-21 03:24
Revised	2026-05-28 08:51
Publication Fee Transferred	2026-06-02 02:50
Second Decision by Editor	2026-06-26 02:16
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-26 05:44
Articles in Press	2026-06-26 05:44
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2220-3206 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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