Publication Name	World Journal of Diabetes
Manuscript ID	121326
DOI	10.4239/wjd.121326
Country	China

Category	Endocrinology & Metabolism
Manuscript Type	Retrospective Cohort Study
Article Title	Peri-colonoscopy hypoglycaemia in type 2 diabetes: Temporal patterns and asymptomatic presentation
Manuscript Source	Unsolicited Manuscript
All Author List	Hai-Yan Yang, Lin-Lin Zhang, Shu-Qiao Hu, Qiu-Ping Yang and De-Liang Liu
Funding Agency and Grant Number	Funding Agency Grant Number Sanming Project of Medicine in Shenzhen No. SZZYSM202411016
Corresponding Author	De-Liang Liu, Associate Professor, Chief Physician, Head, PhD, Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, No. 1 Fuhua Road, Futian District, Shenzhen 518033, Guangdong Province, China. ldl2580@gzucm.edu.cn
Key Words	Type 2 diabetes mellitus; Colonoscopy; Asymptomatic hypoglycaemia; Temporal distribution; Risk stratification; Peri-colonoscopy period; Glucose monitoring; Impaired awareness of hypoglycaemia
Core Tip	This study reveals that more than half (54.1%) of hypoglycaemic events during the peri-colonoscopy period in hospitalised patients with type 2 diabetes mellitus were asymptomatic, representing a substantial monitoring blind spot. Two distinct high-risk windows were identified: (1) The immediate post-colonoscopy phase (highest incidence); and (2) The early bowel preparation period (highest asymptomatic proportion). Diabetes-related retinopathy and nocturnal occurrence were independently associated with asymptomatic presentation, enabling an exploratory risk stratification from 31.8% to 84.2% asymptomatic proportions. These findings support prospective evaluation of phase-specific, risk-stratified glucose monitoring protocols in hospitalised patients.
Citation	Yang HY, Zhang LL, Hu SQ, Yang QP, Liu DL. Peri-colonoscopy hypoglycaemia in type 2 diabetes: Temporal patterns and asymptomatic presentation. World J Diabetes 2026; In press DOI: https://doi.org/10.4239/wjd.121326
PDF	121326-in-press.pdf

Received	2026-03-23 00:36
Peer-Review Started	2026-03-26 09:40
First Decision by Editorial Office Director	2026-04-10 08:09
Return for Revision	2026-04-10 08:09
Revised	2026-04-22 03:21
Publication Fee Transferred
Second Decision by Editor	2026-06-10 02:35
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-22 09:00
Articles in Press	2026-06-22 09:00
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9358 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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