Publication Name	World Journal of Radiology
Manuscript ID	121348
Country	China

Category	Oncology
Manuscript Type	Retrospective Study
Article Title	Portal vein embolization for arterio-portal shunt closure in hepatocellular carcinoma to facilitate selective internal radiation therapy
Manuscript Source	Unsolicited Manuscript
All Author List	Xue Liu, Jin-Yan Zhao, Zhen-Yuan Xu, Shu-Qun Shen, Zhi-Jia Xu, Ye-Fa Yang, Nai-Jian Ge and Xiang-Dong Wang
Funding Agency and Grant Number	Funding Agency Grant Number Clinical Research Cultivation Programa from Shanghai Eastern Hepatobiliary Surgery Hospital No.2023LC004
Corresponding Author	Xiang-Dong Wang, Department of Interventional Radiology, Shanghai Eastern Hepatobiliary Surgery Hospital, No. 700 Moyu North Road, Shanghai 200438, China. 15502106056@163.com
Key Words	Hepatocellular carcinoma; Portal vein embolization; Arterio-portal shunt; Hepatopulmonary shunt; Macroaggregated albumin; Selective internal radiation therapy
Core Tip	Marked arterio-portal shunt (APS) can be a contraindication for selective internal radiation therapy (SIRT) due to the risk of radiation-induced liver toxicity or pneumonitis. In this study, portal vein embolization (PVE) was performed to close the APS outlet in seven hepatocellular carcinoma (HCC) patients, with complete occlusion achieved in six (n = 6, 6/7). Five patients subsequently completed SIRT. PVE is a safe and effective strategy to reduce intrahepatic shunting in advanced HCC patients with APS, thereby improving eligibility for SIRT.
Citation	Liu X, Zhao JY, Xu ZY, Shen SQ, Xu ZJ, Yang YF, Ge NJ, Wang XD. Portal vein embolization for arterio-portal shunt closure in hepatocellular carcinoma to facilitate selective internal radiation therapy. World J Radiol 2026; In press

Received	2026-04-07 05:49
Peer-Review Started	2026-04-07 05:52
First Decision by Editorial Office Director	2026-04-13 09:46
Return for Revision	2026-04-16 12:40
Revised	2026-05-23 08:03
Publication Fee Transferred
Second Decision by Editor	2026-06-23 02:17
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-23 02:50
Articles in Press	2026-06-23 02:50
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1949-8470 (online)
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