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Publication Name World Journal of Hepatology
Manuscript ID 121392
Country China
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Recurrent pruritus, jaundice, and pancreatitis in an adult due to a rare etiology: A case report
Manuscript Source Unsolicited Manuscript
All Author List Jing Zuo, Li-Yuan Wang and Yu-Chen Fan
Funding Agency and Grant Number
Funding Agency Grant Number
the Clinical Research Centre of Shandong University 2021SDUCRCB006
the National Key Research and Development Program of China 2023YFF0718804
Corresponding Author Yu-Chen Fan, Department of Hepatology, Qilu Hospital of Shandong University, Wenhuaxi Road 107#, Jinan 250012, Shandong Province, China. fanyuchen@sdu.edu.cn
Key Words Benign recurrent intrahepatic cholestasis type 1; Progressive familial intrahepatic cholestasis type 1; Adenosine triphosphatase phospholipid transporting 8B1; FIC1; Cholestasis; Case report
Core Tip This case represents the first report of potential pathogenicity for the c.3015G>A variant, providing novel support for clinical screening in benign recurrent intrahepatic cholestasis type 1 (BRIC1). The patient presented with a relatively rare phenotype of BRIC1, characterized by recurrent pancreatitis and hearing loss alongside hepatic involvement. The clinical course suggests a potential role for glucocorticoids in the personalized management of patients with such phenotypes.
Citation Zuo J, Wang LY, Fan YC. Recurrent pruritus, jaundice, and pancreatitis in an adult due to a rare etiology: A case report. World J Hepatol 2026; In press
Received
2026-03-24 02:24
Peer-Review Started
2026-03-24 02:24
First Decision by Editorial Office Director
2026-04-08 09:06
Return for Revision
2026-04-10 05:11
Revised
2026-05-08 12:49
Publication Fee Transferred
2026-05-10 13:52
Second Decision by Editor
2026-06-01 02:41
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2026-06-01 09:47
Articles in Press
2026-06-01 09:47
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright ©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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