| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Retrospective Study |
| Article Title |
Artificial intelligence-based chest computed tomography assessment of bone, vascular, and epicardial adipose changes in type 2 diabetes
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yuan-Kang Liu, Fan-Yu Wu, Cui-Ping Jiang, Yu-Xuan Xia, Ying Li, Wen-Wen Zeng, Shu-Ya Zhang, Dan-Ni Fan, Meng-Xin Zhang, Tong-Chi Liu, Xiao-Ping Wu, Yue Dong, Wen Chen, Ying-Hua Zhao, Tao Li, Zhen Li and Xiang-Yang Xu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Research and Development Program of China |
No. 2024YFC2419300 |
| National Natural Science Foundation of China |
No. 62131009 |
|
| Corresponding Author |
Xiang-Yang Xu, PhD, Department of Radiology, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 39 Yanhu Avenue, Wuchang District, Wuhan 430077, Hubei Province, China. 1993ly0538@hust.edu.cn |
| Key Words |
Type 2 diabetes mellitus; Chest computed tomography; Artificial intelligence; Bone mineral density; Coronary artery calcification; Epicardial adipose tissue |
| Core Tip |
We developed an artificial intelligence-based opportunistic chest computed tomography framework that simultaneously quantifies bone mineral density, coronary artery calcification, and epicardial adipose tissue in type 2 diabetes mellitus. The study reveals a linear bone mineral density-epicardial adipose tissue (EAT) volume association, a linear EAT density-severe coronary artery calcification association, and a J-shaped bone mineral density-EAT density relationship, supporting routine chest computed tomography as a one-stop tool for multisystem risk stratification in diabetes. |
| Citation |
Liu YK, Wu FY, Jiang CP, Xia YX, Li Y, Zeng WW, Zhang SY, Fan DN, Zhang MX, Liu TC, Wu XP, Dong Y, Chen W, Zhao YH, Li T, Li Z, Xu XY. Artificial intelligence-based chest computed tomography assessment of bone, vascular, and epicardial adipose changes in type 2 diabetes. World J Diabetes 2026; In press
|
| PDF |
121422-in-press.pdf
|
