Publication Name	World Journal of Clinical Oncology
Manuscript ID	121461
DOI	10.5306/wjco.121461
Country	China

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Retrospective Study
Article Title	Determinants of magnetic resonance imaging overstaging in rectal cancer T-staging
Manuscript Source	Unsolicited Manuscript
All Author List	Dong-Bing Zhou, Jing Yu, Si-Jia He, Qing Teng, Qing Guo and Quan-Lin Li
Funding Agency and Grant Number
Corresponding Author	Quan-Lin Li, Affiliate Associate Professor, MD, Department of General Surgery, Beijing Anzhen Nanchong Hospital, Capital Medical University and Nanchong Central Hospital, No. 99 Anzhen Road, Gaoping District, Nanchong 637000, Sichuan Province, China. 645185541@qq.com
Key Words	Magnetic resonance imaging; Rectal cancer; T staging; Overstaging; Reader-related factors
Core Tip	Current data indicate a propensity for magnetic resonance imaging to overestimate the T category of rectal tumors, particularly when evaluating diminutive lesions, polypoid morphologies, or cases demonstrating pronounced post-neoadjuvant regression. Diagnostic precision was concurrently compromised by several interpreter variables; restricted clinical tenure, absent structured training, abbreviated review durations, and solitary reading without multidisciplinary team input all exacerbated staging inaccuracies. Consequently, such observations advocate for adopting a risk-stratified clinical paradigm. For these vulnerable scenarios, standard magnetic resonance imaging assessments require augmentation through endorectal ultrasonography alongside cross-specialty panel consensus.
Citation	Zhou DB, Yu J, He SJ, Teng Q, Guo Q, Li QL. Determinants of magnetic resonance imaging overstaging in rectal cancer T-staging. World J Clin Oncol 2026; In press DOI: https://doi.org/10.5306/wjco.121461
PDF	121461-in-press.pdf

Received	2026-03-26 02:24
Peer-Review Started	2026-03-26 02:24
First Decision by Editorial Office Director	2026-04-17 08:07
Return for Revision	2026-04-17 08:07
Revised	2026-05-04 02:40
Publication Fee Transferred	2026-05-09 10:41
Second Decision by Editor	2026-06-08 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-08 09:39
Articles in Press	2026-06-08 09:39
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
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