Publication Name	World Journal of Clinical Oncology
Manuscript ID	121496
DOI	10.5306/wjco.121496
Country	China

Category	Oncology
Manuscript Type	Case Report
Article Title	Lymph node extramedullary hematopoiesis in breast cancer patients receiving neoadjuvant chemotherapy combined with immunotherapy: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Ping Xing, Zhi-Gang Chen, Hai-Li Jin, Hua-Rong Luo, Mei-Fu Gan and Jian Huang
Funding Agency and Grant Number
Corresponding Author	Mei-Fu Gan, Department of Pathology, Taizhou Hospital of Zhejiang Province, Department of Pathology, Taizhou Hospital, Taizhou 318000, China; E-mail: Ganmf@enzemed.com., Linhai 318000, Zhejiang Province, China. ganmf@enzemed.com
Key Words	Breast cancer; Neoadjuvant immuno-chemotherapy; PD-1 inhibitor; Extramedullary hematopoiesis; Axillary lymph node
Core Tip	This is the first case report of trilineage extramedullary hematopoiesis (EMH) in axillary lymph nodes after neoadjuvant chemoimmunotherapy with a PD-1 inhibitor for triple-negative breast cancer. It highlights a benign mimic of malignancy, emphasizes granulocyte colony-stimulating factor as an initiator of EMH, and speculatively links PD-1 blockade to EMH persistence. Recognition prevents misdiagnosis and underscores systemic therapy effects.
Citation	Xing P, Chen ZG, Jin HL, Luo HR, Gan MF, Huang J. Lymph node extramedullary hematopoiesis in breast cancer patients receiving neoadjuvant chemotherapy combined with immunotherapy: A case report. World J Clin Oncol 2026; In press DOI: https://doi.org/10.5306/wjco.121496
PDF	121496-in-press.pdf

Received	2026-03-30 02:56
Peer-Review Started	2026-03-31 06:59
First Decision by Editorial Office Director	2026-04-15 08:03
Return for Revision	2026-04-15 08:03
Revised	2026-05-05 07:02
Publication Fee Transferred	2026-05-09 09:19
Second Decision by Editor	2026-06-04 02:54
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-04 08:45
Articles in Press	2026-06-04 08:45
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2218-4333 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com