Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	121498
Country	China

Category	Pediatrics
Manuscript Type	Retrospective Study
Article Title	Clinical characteristics of hospitalized children with gastrointestinal bleeding and risk factors for associated anemia
Manuscript Source	Unsolicited Manuscript
All Author List	Yun Yao, Yan Hu, Yi Chen, Yu-Ping Wang and Chuan-Ying Li
Funding Agency and Grant Number
Corresponding Author	Chuan-Ying Li, Academic Fellow, Pediatric Gastroenterology, Anhui Children's Hospital, No. 39 Wangjiang East Road, Tong'an Street, Baohe District, Hefei 230051, Anhui Province, China. licy693@163.com
Key Words	Gastrointestinal bleeding; Anemia; Clinical characteristics; Coagulation function; Risk factor
Core Tip	This single-center retrospective study of 257 hospitalized children found an anemia incidence of 17.5%. Key independent risk factors for anemia included melena, low albumin levels, low lymphocyte count, and shortened activated partial thromboplastin time (APTT). Diarrhea was identified as a protective factor. Notably, shortened APTT, rather than prolonged APTT, emerged as a novel independent risk factor, suggesting a possible compensatory coagulation response to chronic bleeding. These findings highlight the necessity of early identification of high-risk children to enable timely intervention.
Citation	Yao Y, Hu Y, Chen Y, Wang YP, Li CY. Clinical characteristics of hospitalized children with gastrointestinal bleeding and risk factors for associated anemia. World J Gastrointest Surg 2026; In press

Received	2026-04-02 09:46
Peer-Review Started	2026-04-02 09:46
First Decision by Editorial Office Director	2026-04-16 07:27
Return for Revision	2026-04-16 07:27
Revised	2026-04-28 10:23
Publication Fee Transferred	2026-04-30 12:33
Second Decision by Editor	2026-05-09 02:37
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-09 13:29
Articles in Press	2026-05-09 13:29
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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