Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	121571
DOI	10.4291/wjgp.121571
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Advancing the understanding of eosinophilic esophagitis: From pathogenesis to novel therapies
Manuscript Source	Invited Manuscript
All Author List	Ashish Sharma, Angad Tiwari, Vishal Deshpande, Vishal Abhimutt Mahesh, Harendra Kumar, Anuj Shah, Ishita Ray, Rajvardhan Sisodia, Sneh Sonaiya, Saqr Alsakarneh, Hassam Ali and Dushyant Singh Dahiya
Funding Agency and Grant Number
Corresponding Author	Dushyant Singh Dahiya, MD, Division of Gastroenterology, Hepatology and Motility, University of Kansas School of Medicine, 2000 Olathe Boulevard, Kansas City, KS 66160, United States. dush.dahiya@gmail.com
Key Words	Eosinophilic esophagitis; Dysphagia; Dupilumab; Biologic therapy; Elimination diet; Esophageal eosinophilia; Endoscopic dilation
Core Tip	Eosinophilic esophagitis is increasingly recognized as a progressive fibrostenotic disease in which symptom severity may not correlate with histologic activity, contributing to diagnostic delays and long-term esophageal remodeling. New imaging modalities including functional luminal imaging probe, Cytosponge, and artificial intelligence driven histologic scoring have shown promise in assessing disease beyond eosinophilic counts. Precision medicine approaches and endotype driven therapies are expected to transform patient management in the near future.
Citation	Sharma A, Tiwari A, Deshpande V, Mahesh VA, Kumar H, Shah A, Ray I, Sisodia R, Sonaiya S, Alsakarneh S, Ali H, Dahiya DS. Advancing the understanding of eosinophilic esophagitis: from pathogenesis to novel therapies. World J Gastrointest Pathophysiol 2026; In press DOI: https://doi.org/10.4291/wjgp.121571
PDF	121571-in-press.pdf

Received	2026-03-27 03:01
Peer-Review Started	2026-03-27 03:02
First Decision by Editorial Office Director	2026-05-14 01:11
Return for Revision	2026-05-14 01:11
Revised	2026-06-01 05:33
Publication Fee Transferred
Second Decision by Editor	2026-06-17 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-06-17 06:05
Articles in Press	2026-06-17 06:05
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2150-5330 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© Author(s) (or their employer(s)) 2026. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com