Publication Name	World Journal of Methodology
Manuscript ID	121596
Country	Spain

Category	Dentistry, Oral Surgery & Medicine
Manuscript Type	Observational Study
Article Title	Salivary glutathione peroxidase-1 levels in periodontitis
Manuscript Source	Invited Manuscript
All Author List	Leonardo Lorente, Esther Hernández Marrero, Pedro Abreu-Gonzalez, Angel Daniel Lorente Martín, Marina Lorente Martín, María José Marrero González, Carmen Hernández Marrero, Olga Hernández Marrero, Alejandro Jiménez and Cándido Manuel Hernández Padilla
Funding Agency and Grant Number
Corresponding Author	Leonardo Lorente, MD, PhD, Intensive Care Unit, Hospital Universitario de Canarias, Ofra s/n, San Cristóbal de La Laguna 38320, Tenerife, Spain. lorentemartin@msn.com
Key Words	Glutathione peroxidase; Salivary; Periodontitis; Oxidation; Severity; Diagnosis
Core Tip	Periodontitis consists of a chronic inflammatory disease of periodontal tissue. In addition to inflammation, oxidation is also involved in periodontitis. Glutathione peroxidase (GPx)-1 is an antioxidant enzyme. Novel findings of our study were that salivary GPx-1 levels were able to diagnose periodontitis and were independently associated with periodontitis.
Citation	Lorente L, Hernández Marrero E, Abreu-Gonzalez P, Lorente Martín AD, Lorente Martín M, Marrero González MJ, Hernández Marrero C, Hernández Marrero O, Jiménez A, Hernández Padilla CM. Salivary glutathione peroxidase-1 levels in periodontitis. World J Methodol 2026; In press

Received	2026-03-30 08:13
Peer-Review Started	2026-03-31 01:46
First Decision by Editorial Office Director	2026-04-23 09:09
Return for Revision	2026-04-23 09:09
Revised	2026-04-29 09:01
Publication Fee Transferred
Second Decision by Editor	2026-05-18 02:51
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-18 09:11
Articles in Press	2026-05-18 09:11
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com