Publication Name	World Journal of Clinical Cases
Manuscript ID	121686
Country	Kuwait

Category	Dermatology
Manuscript Type	Case Report
Article Title	Kaposi sarcoma in human immunodeficiency virus infection, clinicopathologic correlation with coexisting patch and plaque stage features: A case report and review of literature
Manuscript Source	Invited Manuscript
All Author List	Khadeja Alrefaie, Al-Sadat Mosbeh and Abeer Albazali
Funding Agency and Grant Number
Corresponding Author	Khadeja Alrefaie, MD, Department of Training, Kuwait Institute for Medical Specializations, Jamal Abdulnaser Street, Sulibekhat 13018, Kuwait. alhoussani6078@moh.gov.kw
Key Words	Kaposi sarcoma; Human herpesvirus 8; Latent nuclear antigen-1; Human immunodeficiency virus; Vascular tumors; Dermatopathology; Case report
Core Tip	Kaposi sarcoma may be the first clinical indicator of previously undiagnosed human immunodeficiency virus infection. This case demonstrates the coexisting histopathologic features of patch and plaque stages within a single biopsy specimen, highlighting key diagnostic features such as slit-like vascular spaces, spindle-cell proliferation, and confirmatory human herpesvirus 8 latent nuclear antigen-1 positivity. Recognition of these clinicopathological features is essential for differentiating Kaposi sarcoma from its mimickers and enables timely human immunodeficiency virus testing and early initiation of antiretroviral therapy, which may lead to lesion regression and improved clinical outcomes.
Citation	Alrefaie K, Mosbeh AS, Albazali A. Kaposi sarcoma in human immunodeficiency virus infection, clinicopathologic correlation with coexisting patch and plaque stage features: A case report and review of literature. World J Clin Cases 2026; In press

Received	2026-03-31 03:49
Peer-Review Started	2026-03-31 03:52
First Decision by Editorial Office Director	2026-04-13 08:33
Return for Revision	2026-04-13 08:33
Revised	2026-05-03 14:53
Publication Fee Transferred
Second Decision by Editor	2026-05-25 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-05-25 08:26
Articles in Press	2026-05-25 08:26
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	2307-8960 (online)
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