Publication Name	World Journal of Gastroenterology
Manuscript ID	121707
Country	Spain

Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Assessment of metabolic biomarkers associated with hepatic steatosis in Crohn’s disease
Manuscript Source	Unsolicited Manuscript
All Author List	Cristina Suárez Ferrer, Marta Abadía, María Gema Crespo Sanchez, Jose Luis Rueda García, Antonio Olveira, Miriam Romero, Marta Molero-Luis, Eduardo Martin-Arranz, Maria Sanchez-Azofra, Araceli García, Clara Amiama Roig, Joaquín Poza Cordón, Laura García-Ramírez and Maria Dolores Martin-Arranz
Funding Agency and Grant Number	Funding Agency Grant Number Luis Álvarez Grant awarded by the Instituto de Investigación Sanitaria IdiPAZ (IdiPAZ) in 2024
Corresponding Author	Cristina Suárez Ferrer, MD, PhD, Department of Gastroenterology, Hospital La Paz Institute for Health Research (IdiPAZ), La Paz University Hospital, Paseo de la Castellana 261, Madrid 28046, Spain. cristinajsuarezferrer@gmail.com
Key Words	Crohn’s disease; Metabolic dysfunction-associated steatotic liver disease; Hepatic steatosis; Hepatokines; Angiopoietin-like protein 6; Fibroblast growth factor 21; Controlled attenuation parameter; Intestinal inflammation
Core Tip	Active Crohn’s disease is associated with a higher prevalence of steatosis and increased angiopoietin-like protein 6 and fibroblast growth factor 21 levels, suggesting inflammation-related metabolic alterations. Controlled attenuation parameter may serve as a reliable non-invasive tool for steatosis detection in Crohn’s disease, although inflammatory activity should be considered in its interpretation.
Citation	Suárez Ferrer C, Abadía M, Crespo Sanchez MG, Rueda García JL, Olveira A, Romero M, Molero-Luis M, Martin-Arranz E, Sanchez-Azofra M, García A, Amiama Roig C, Poza Cordón J, García-Ramírez L, Martin-Arranz MD. Assessment of metabolic biomarkers associated with hepatic steatosis in Crohn’s disease. World J Gastroenterol 2026; In press

Received	2026-03-31 01:51
Peer-Review Started	2026-03-31 01:54
First Decision by Editorial Office Director	2026-04-10 10:27
Return for Revision	2026-04-10 10:27
Revised	2026-04-20 08:00
Publication Fee Transferred	2026-05-11 16:16
Second Decision by Editor	2026-07-03 02:38
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-07-03 07:22
Articles in Press	2026-07-03 07:22
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com