Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	121745
DOI	10.4251/wjgo.121745
Country	Singapore

Category	Oncology
Manuscript Type	Observational Study
Article Title	Evolving practices, treatment decisions, and unmet needs in intermediate-stage hepatocellular carcinoma: An Asia Pacific perspective
Manuscript Source	Unsolicited Manuscript
All Author List	Suebpong Tanasanvimon, Pin-Nan Cheng, Wonseok Kang, Gwo-Fuang Ho, Tuan-Anh Pham, Michael Cabato, Ryan Edbert Husni, Bo-Young Kim and Pierce Chow
Funding Agency and Grant Number
Corresponding Author	Pierce Chow, Department of Hepato-Pancreato-Biliary Surgery and Transplantation, National Cancer Centre Singapore, Singapore General Hospital, Singapore 169608, Singapore. pierce.chow@duke-nus.edu.sg
Key Words	Intermediate hepatocellular carcinoma; Hepatocellular carcinoma; Systemic therapy; Locoregional therapy; Survey; Physician survey
Core Tip	The integration of systemic therapy with locoregional therapy (LRT) for the treatment of intermediate-stage hepatocellular carcinoma (iHCC) is rapidly becoming an area of interest. In this physician-targeted survey, 98.1% of prescribers had experience using a systemic therapy in combination or sequence with LRT for the treatment of iHCC. Patients with Barcelona Clinic Liver Cancer stage B2 and B3 iHCC were seen as ideal candidates for such combinations; however, barriers to access included lack of evidence for combination-therapy use and cost/reimbursement status of approved treatments.
Citation	Tanasanvimon S, Cheng PN, Kang W, Ho GF, Pham TA, Cabato M, Husni RE, Kim BY, Chow P. Evolving practices, treatment decisions, and unmet needs in intermediate-stage hepatocellular carcinoma: An Asia Pacific perspective. World J Gastrointest Oncol 2026; In press DOI: https://doi.org/10.4251/wjgo.121745
PDF	121745-in-press.pdf

Received	2026-04-01 02:49
Peer-Review Started	2026-04-01 02:49
First Decision by Editorial Office Director	2026-06-09 03:14
Return for Revision	2026-06-09 03:14
Revised	2026-07-09 09:33
Publication Fee Transferred	2026-07-24 02:24
Second Decision by Editor	2026-08-25 02:47
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2026-08-25 09:25
Articles in Press	2026-08-25 09:25
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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Copyright	©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
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